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Table 2 Selectivity of the cytotoxicity of anthraquinone derivatives (compound 1–5) to various cancer cells as compared with MDCK cells

From: Cytotoxic properties of the anthraquinone derivatives isolated from the roots of Rubia philippinensis

Compounds

IC50 (μM)a

SK-MEL-5

B16F10

MCF7

MDA-MB-231

1

2.11

3.95

2.94

3.89

2

3.61

2.17

2.11

2.85

3

3.76

2.02

4.05

4.10

4

3.18

2.86

4.31

4.63

5

1.85

2.68

3.28

6.06

  1. aThe selectivity index is the ratio of the IC50 values of the treatments on MDCK cells to those in the cancer cell lines. SK-MEL-5 (human melanoma); B16F10 (murine melanoma); MCF-7 (human breast adenocarcinoma); MDA-MB-231 (human breast adenocarcinoma)
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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