GLP-I secretion in healthy and diabetic Wistar rats in response to aqueous extract of Momordica charantia

Table 6 The effect of long term exposure of Momordica charantia on GLP-1 level in normal and diabetic rats

Time in second	0 min	20 min	30 min	40 min	50 min	60 min
Group I	12.00 ± 0.288	15.20 ± 0.970	14.81 ± 0.788	13.81 ± 0.484	12.30 ± 0.463	12.08 ± 0.422
Group II	15.63 ± 0.841	23.73 ± 1.654^γ***	20.52 ± 1.090^γ***	18.66 ± 0.667 ^α***	17.46 ± 0.507 ^α***	16.33 ± 0.729 ^α***
Group III	5.10 ± 0.289	9.86 ± 0.603^γ***	8.91 ± 0.534^γ***	7.21 ± 0.391^β***	6.35 ± 0.396 ^α***	5.82 ± 0.311 ^α***
Group IV	9.27 ± 0.638	37.72 ± 2.315^γr	31.35 ± 1.704^γr	22.71 ± 0.948^γr	15.10 ± 0.276^βr	10.80 ± 0.600^αr

The values represent as Mean ± SEM for 6 rats each. The results are expressed in pg/mL. α = (P > 0.05), β = (P < 0.05), γ = (P < 0.01) represents comparison of 0 min reading of each group with 20,30,40,50 and 60 min. * = (P > 0.05), ** = (P < 0.05), *** = (P < 0.01) represents comparison of Group-III with Group-I. ^p = P > 0.05), ^q = (P < 0.05), ^r = (P < 0.01) compared Group IV with Group III. Group-I Normal Control; Group-II Normal treated (AEMC); Group-III Diabetic control; Group-IV diabetic treated (AEMC)

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