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Table 6 The effect of long term exposure of Momordica charantia on GLP-1 level in normal and diabetic rats

From: GLP-I secretion in healthy and diabetic Wistar rats in response to aqueous extract of Momordica charantia

Time in second

0 min

20 min

30 min

40 min

50 min

60 min

Group I

12.00 ± 0.288

15.20 ± 0.970

14.81 ± 0.788

13.81 ± 0.484

12.30 ± 0.463

12.08 ± 0.422

Group II

15.63 ± 0.841

23.73 ± 1.654γ***

20.52 ± 1.090γ***

18.66 ± 0.667 α***

17.46 ± 0.507 α***

16.33 ± 0.729 α***

Group III

5.10 ± 0.289

9.86 ± 0.603γ***

8.91 ± 0.534γ***

7.21 ± 0.391β***

6.35 ± 0.396 α***

5.82 ± 0.311 α***

Group IV

9.27 ± 0.638

37.72 ± 2.315γr

31.35 ± 1.704γr

22.71 ± 0.948γr

15.10 ± 0.276βr

10.80 ± 0.600αr

  1. The values represent as Mean ± SEM for 6 rats each. The results are expressed in pg/mL. α = (P > 0.05), β = (P < 0.05), γ = (P < 0.01) represents comparison of 0 min reading of each group with 20,30,40,50 and 60 min. * = (P > 0.05), ** = (P < 0.05), *** = (P < 0.01) represents comparison of Group-III with Group-I. p = P > 0.05), q = (P < 0.05), r = (P < 0.01) compared Group IV with Group III. Group-I Normal Control; Group-II Normal treated (AEMC); Group-III Diabetic control; Group-IV diabetic treated (AEMC)