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Table 5 The effect of single dose of Momordica charantia on GLP-1 level in normal and diabetic Wistar rats

From: GLP-I secretion in healthy and diabetic Wistar rats in response to aqueous extract of Momordica charantia

Time in second

0 min

20 min

30 min

40 min

50 min

60 min

Group I

12.00 ± 0.288

15.20 ± 0.970

14.81 ± 0.788

13.81 ± 0.484

12.30 ± 0.463

12.08 ± 0.422

Group II

12.15 ± .669

20.00 ± 1.403β***

17.28 ± 0.967α***

15.23 ± 0.871α*

14.75 ± 0.963α*

13.65 ± 1.007α*

Group III

5.10 ± 0.289

9.86 ± 0.603 γ***

8.91 ± 0.534 γ***

7.21 ± 0.391 β***

6.35 ± 0.396α***

5.82 ± 0.311α***

Group IV

5.58 ± 0.733

11.80 ± 1.562γp

10.65 ± 1.327γp

8.61 ± 1.069αp

7.51 ± 0.938αp

6.46 ± 0.820αp

  1. The values represent as Mean ± SEM for 6 rats each. The results are expressed in pg/mL. α = (P > 0.05), β = (P < 0.05), γ = (P < 0.01) represents comparison of 0 min reading of each group with 20,30,40,50 and 60 min. * = (P > 0.05), ** = (P < 0.05), *** = (P < 0.01) represents comparison of Group-III with Group-I. p = P > 0.05), q = (P < 0.05), r = (P < 0.01) compared Group IV with Group III. Group-I Normal Control; Group-II Normal treated (AEMC); Group-III Diabetic control; Group-IV diabetic treated (AEMC)