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Table 5 The effect of single dose of Momordica charantia on GLP-1 level in normal and diabetic Wistar rats

From: GLP-I secretion in healthy and diabetic Wistar rats in response to aqueous extract of Momordica charantia

Time in second 0 min 20 min 30 min 40 min 50 min 60 min
Group I 12.00 ± 0.288 15.20 ± 0.970 14.81 ± 0.788 13.81 ± 0.484 12.30 ± 0.463 12.08 ± 0.422
Group II 12.15 ± .669 20.00 ± 1.403β*** 17.28 ± 0.967α*** 15.23 ± 0.871α* 14.75 ± 0.963α* 13.65 ± 1.007α*
Group III 5.10 ± 0.289 9.86 ± 0.603 γ*** 8.91 ± 0.534 γ*** 7.21 ± 0.391 β*** 6.35 ± 0.396α*** 5.82 ± 0.311α***
Group IV 5.58 ± 0.733 11.80 ± 1.562γp 10.65 ± 1.327γp 8.61 ± 1.069αp 7.51 ± 0.938αp 6.46 ± 0.820αp
  1. The values represent as Mean ± SEM for 6 rats each. The results are expressed in pg/mL. α = (P > 0.05), β = (P < 0.05), γ = (P < 0.01) represents comparison of 0 min reading of each group with 20,30,40,50 and 60 min. * = (P > 0.05), ** = (P < 0.05), *** = (P < 0.01) represents comparison of Group-III with Group-I. p = P > 0.05), q = (P < 0.05), r = (P < 0.01) compared Group IV with Group III. Group-I Normal Control; Group-II Normal treated (AEMC); Group-III Diabetic control; Group-IV diabetic treated (AEMC)
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