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Table 4 The effect of sub-chronic administration of Momordica charantia on Serum insulin level in normal and diabetic Wistar rats

From: GLP-I secretion in healthy and diabetic Wistar rats in response to aqueous extract of Momordica charantia

Time in second

0 min

20 min

30 min

40 min

50 min

60 min

Group I

4.10 ± 0.217

4.20 ± 0.206

4.17 ± 0.210

4.16 ± 0.211

4.14 ± 0.211

4.12 ± 0.212

Group II

4.16 ± 0.301

5.60 ± 0.263α*

5.46 ± 0.278α*

4.37 ± 0.296α*

4.28 ± 0.292α*

4.18 ± 0.299α*

Group III

1.25 ± 0.239

1.39 ± 0.194α***

1.36 ± 0.205α***

1.34 ± 0.207α***

1.30 ± 0.219α***

1.25 ± 0.234α**

Group IV

2.82 ± 0.136

5.22 ± 0.273γr

4.48 ± 0.310γr

4.05 ± 0.310βr

3.36 ± 0.204αr

3.05 ± 0.195αr

  1. The values represent as Mean ± SEM for 6 rats each. The results are expressed in ng/mL. α = (P > 0.05), β = (P < 0.05), γ = (P < 0.01) represents comparison of 0 min reading of each group with 20,30,40,50 and 60 min. * = (P > 0.05), ** = (P < 0.05), *** = (P < 0.01) represents comparison of Group-II, III with Group-I. p = P > 0.05), q = (P < 0.05), r = (P < 0.01) compared Group IV with Group III. Group-I Normal Control; Group-II Normal treated (AEMC); Group-III Diabetic control; Group-IV diabetic treated (AEMC)