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Table 1 Chemical composition of tested essential oils as determined by GC-MS analysis

From: Use of Pinus sylvestris L. (Pinaceae), Origanum vulgare L. (Lamiaceae), and Thymus vulgaris L. (Lamiaceae) essential oils and their main components to enhance itraconazole activity against azole susceptible/not-susceptible Cryptococcus neoformans strains

Number

Componenta

LRIb

Origanum vulgare %

Pinus sylvestris %

Thymus vulgaris %

1

α-Thujene

926

0.34

0.02

0.27

2

α-Pinene

933

0.95

55.76

11.50

3

Camphene

947

0.17

1.79

1.10

4

Sabinene

973

–

0.13

–

5

β-Pinene

979

0.60

9.034

0.77

6

β-Myrcene

992

2.34

3.41

1.30

7

α-Phellandrene

1004

0.17

0.19

0.10

8

δ-3-Carene

1009

–

6.96

1.30

9

α-Terpinene

1017

1.08

0.47

0.49

10

p-Cymene

1025

12.36

2.01

16.26

11

Limonene

1029

0.54

9.74

13.20

12

1,8-Cineole

1033

–

–

1.29

13

trans-Ocimene

1048

–

0.03

0.03

14

γ –Terpinene

1059

7.60

0.10

4.02

15

Terpinolene

1088

–

0.81

0.40

16

cis-Sabinene hydrate

1098

–

0.06

0.13

17

trans-Pinocarveol

1140

–

0.12

–

18

Camphor

1144

–

0.07

1.37

19

Borneol

1166

–

0.12

0.69

20

Terpinen-4-ol

1179

0.86

0.21

0.63

21

p-Cymen-8-ol

1186

–

0.25

0.04

22

α-Terpineol

1192

–

0.87

1.22

23

Verbenone

1210

–

0.07

–

24

Bornyl-acetate

1289

–

0.95

–

25

Thymol

1295

5.12

–

26.52

26

Carvacrol

1305

62.61

–

7.85

27

α-Cububene

1355

–

0.11

–

28

α-Copaene

1381

–

0.14

–

29

β-Caryophyllene

1425

0.89

0.94

1.34

30

α-Humulene

1460

–

0.11

–

31

γ –Muurolene

1481

–

0.06

–

32

Caryophyllene oxide

1593

1.01

–

–

  1. aCompounds are listed in order of elution
  2. bLinear retention index (LRI) calculated on HP-5 column