Fig. 4

Protection of Hepa-1c1c7 cells against menadione-induced cytotoxicity. Hepa-1c1c7 cells were pretreated with either DMSO or 3.125 μM from indicated compounds for 24 h before being intoxicated with 20 μM of menadione (MD) for a further 24 h. Cell monolayers were then fixed with TCA for 1 h and processed for SRB cytotoxicity assay. Data are means of at least quadrate treatments for each concentration