Table 2 Patient Daily Diary changes over 28-day intervention (percentages represent proportion of participants for each measure)
Herbagut | Placebo | |||||
|---|---|---|---|---|---|---|
Baseline | Day 14 | Day 28 | Baseline | Day 14 | Day 28 | |
≥ 3 BOWEL MOVEMENTS PER WEEK | 12% | 28% | 72% | 4% | 4% | 4% |
BRISTOL RATINGS | ||||||
Type 1 & 2 (constipation) | 100% | 36% | 24% | 100% | 60% | 52% |
Type 3 & 4 (healthy stool) | 0% | 64% | 44% | 0% | 24% | 32% |
Type 5 (precursor to diarrhoea) | 0% | 0% | 28% | 0% | 16% | 12% |
Type 6 & 7 (diarrhoea) | 0% | 0% | 4% | 0% | 0% | 4% |
EASE OF BOWEL MOVEMENTS | ||||||
Manual disimpaction | 56% | 8% | 16% | 32% | 32% | 32% |
Enema needed | 32% | 16% | 0% | 36% | 24% | 32% |
Straining | 0% | 4% | 0% | 24% | 24% | 24% |
Normal | 0% | 56% | 76% | 4% | 8% | 4% |
Urgent without pain | 0% | 12% | 8% | 0% | 8% | 0% |
Urgent with pain | 12% | 4% | 0% | 4% | 4% | 8% |
INCOMPLETE EVACUATION | 84% | 24% | 24% | 92% | 72% | 76% |