From: The mutagenic and antimutagenic activity of Sutherlandia frutescens extracts and marker compounds
Extract | *conc. (%) | TA97a | TA98 | TA100 | TA102 | ||||
---|---|---|---|---|---|---|---|---|---|
(-S9) | (+S9) | (-S9) | (+S9) | (-S9) | (+S9) | (-S9) | (+S9) | ||
MeOH | 10 | 214 ± 3 | 237 ± 4 | 63 ± 3 | 69 ± 1 | 171 ± 3 | 184 ± 4 | 314 ± 61 | 387 ± 47 |
50 | 191 ± 5 | 203 ± 3 | 77 ± 3 | 92 ± 5 | 117 ± 4 | 132 ± 5 | 264 ± 48 | 365 ± 9 | |
EA | 5 | 216 ± 3 | 271 ± 7 | 45 ± 3 | 53 ± 3 | 204 ± 3 | 221 ± 4 | 209 ± 21 | 297 ± 22 |
20 | 191 ± 5 | 202 ± 2 | 63 ± 1 | 69 ± 1 | 174 ± 3 | 184 ± 3 | 210 ± 34 | 288 ± 25 | |
Spontaneous revertants | 185 ± 3 | 138 ± 5 | 31 ± 2 | 44 ± 3 | 102 ± 4 | 119 ± 2 | 185 ± 32 | 216 ± 41 | |
Common Valid Range [39] | 75-200 | 100-200 | 20-50 | 20-50 | 75-200 | 75-200 | 100-300 | 200-400 | |
Revertant counts (Positive#control) | 369 ± 5 (9-AA) | 256 ± 6 (2-AAF) | 373 ± 5 (AFB1) | 997 ± 99 (CHP) |