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Table 3 Inhibitory effect of indomethacin on plasma electrolyte level induced by EFPA in rats

From: The acute diuretic effect of an ethanolic fraction of Phyllanthus amarus (Euphorbiaceae) in rats involves prostaglandins

Groups

Plasma levels (mEq/L)

Na+

Cl−

K+

Ca2+

Control

114.70 ± 5.51

104.33 ± 3.90

70.50 ± 2.90

5.40 ± 2.52

EFPA (10 mg/kg)

125.50 ± 4.00

102.00 ± 4.32

54.70 ± 2.80*

5.21 ± 2.60

EFPA (10 mg/kg) + Indomethacin (5 mg/kg)

119.33 ± 4.43

103.33 ± 3.41

50.83 ± 5.10*

5.13 ± 2.54

  1. Rats were treated over a 24 h period with a single dose of either vehicle (control group), EFPA (10 mg/kg) or EFPA (10 mg/kg) + indomethacin (5 mg/kg, 1 h pretreatment) administered i.p. Data are given as means ± SEM of 6 different experiments. Statistical analyses were assessed using two-way analysis of variance (ANOVA) followed by Bonferroni’s post- test. *p < 0.05 versus control, and #p < 0.05 versus EFPA
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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