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Table 2 IC50 Values of 90% methanolic extracts and its derived fractions for AChE, BuChE, α– and β–Glucosidase inhibition assays

From: Phytochemical profiling and in vitro screening for anticholinesterase, antioxidant, antiglucosidase and neuroprotective effect of three traditional medicinal plants for Alzheimer’s Disease and Diabetes Mellitus dual therapy

Plant Extract IC50 Values (μg/mL)
AChE BuChE α–Glc β–Glc
B.axillaris 90% MeOH 4.96 ± 0.96 7.5 ± 0.49 17.14 ± 1.9 25.94 ± 0.4
CHCl3 12.29 ± 2.14 9.94 ± 2.14 16.65 ± 1.99 27.38 ± 1.24
n-BuOH 67.51 ± 4.81 168.62 ± 39.5 86.61 ± 5.32 270.95 ± 34.09
H2O 136.21 ± 8.2 245.1 ± 35.2 244.66 ± 12.8 387.59 ± 37.8
H.indicus 90% MeOH 48.64 ± 11.72 3.8 ± 0.2 9.33 ± 0.2 62.91 ± 6.66
CHCl3 28.14 ± 0.9 5.16 ± 0.22 11.03 ± 0.5 87.64 ± 15.41
n-BuOH 113.49 ± 11.07 276.74 ± 13.4 220.75 ± 12.4 139.8 ± 15.73
H2O 129.43 ± 8.6 76.62 ± 4.4 70.12 ± 2.13 87.5 ± 5.10
R.mysorensis 90% MeOH 21.73 ± 0.3 6.93 ± 0.4 70.11 ± 1.9 32.26 ± 3.4
CHCl3 41.35 ± 1.6 15.86 ± 7.3 26.04 ± 0.37 25.33 ± 0.3
n-BuOH 83.55 ± 2.8 208.2 ± 22.3 125.61 ± 4.24 238.89 ± 24.88
H2O 93.67 ± 2.3 120.15 ± 14.6 360.07 ± 91.3 590.49 ± 80.9
Galantamine 0.77 ± 0.09 8.1 ± 0.02
Acarbose 117.20 ± 0.017
D-Glucono-δ-lactone 10.68 ± 0.005