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Table 2 Effect of extracts of Zanthoxylum armatum and standard drug Glibenclamide on glucose level of normal and alloxan induced diabetic mice

From: Zanthoxylum armatum DC extracts from fruit, bark and leaf induce hypolipidemic and hypoglycemic effects in mice- in vivo and in vitro study

Groups

Glucose level (mg/dl)

Oth day

3rd day

6th day

9th day

12th day

15th day

% variance

Normal control

110.5 ± 14

99.83 ± 17

99.33 ± 18

102.2 ± 28

107.5 ± 3

109.2 ± 2

4.69%

Diabetic control

333.7 ± 1*

344.0 ± 2*

345.3 ± 22*

335.8 ± 40*

358.0 ± 20*

374.7 ± 16*

6.80%

Normal Zf treated

111.2 ± 13

107.5 ± 15

104.5 ± 16

98.67 ± 14

98.33 ± 14

78.83 ± 34**

11.46%

Diabetic Zf treated

334.2 ± 44.6

298.0 ± 1*

255.8 ± 25*

250.0 ± 30*

234.8 ± 2*

215.8 ± 30*

16.48%

Normal Zb. Treated

114.0 ± 15.

109.7 ± 13

112.7 ± 13

101.3 ± 12

94.67 ± 10

94.5 ± 12

8.47%

Diabetic Zb treated

279.8 ± 36

265.8 ± 3*

259.2 ± 38*

252.2 ± 35*

246.3 ± 3*

239.2 ± 33*

5.65%

Normal Zl treated

106.8 ± 17

105.3 ± 15

108.8 ± 17

99.6 ± 14

100.2 ± 11

98.83 ± 14

4.09%

Diabetic Zl treated

325.2 ± 26

234.0 ± 3*

188.8 ± 36*

154.0 ± 23*

147.5 ± 2*

123.7 ± 18*

37.95%

Diabetic Glibenclamide treated

320.7 ± 22

271.5 ± 18*

215.7 ± 18*

154.2 ± 18*

163.0 ± 1*

136.3 ± 17*

34.84%

  1. Data represented as mean ± S.D. values of 6 animals each *p < 0.001, **p < 0.05 (One way ANOVA, Dunnet’s t-test, Graph pad prism software). Normal control was compared with normal control. and extract treated. The Diabetic control was compared with diabetic extract treated and standard