Zanthoxylum armatum DC extracts from fruit, bark and leaf induce hypolipidemic and hypoglycemic effects in mice- in vivo and in vitro study

Table 1 Effect of extracts of Zanthoxylum armatum and standard drug Glibenclamide on body weight of normal and alloxan monohydrate induced diabetic mice

Groups	Body weight in grams
Groups	Before treatment	After 7 days	After 15 days	% Variation
Normal	27.67 ± 2.3	30.83 ± 4.3	34.33 ± 6.3	10.77%
Diabetic control	32 ± 1.8	28 ± 3.0	25 ± 3.8**	12.39%
Normal Zf treated	29.67 ± 2.33	31.33 ± 2.50	33.83 ± 2.04**	6.62%
Diabetic Zf treated	31 ± 1.1	25 ± 1.8	26 ± 2.4	12.81%
Normal Zb. Treated	29.67 ± 2.33	31.00 ± 2.09	33.00 ± 2.09**	5.37%
Diabetic Zb treated	30.00 ± 2.82	28.83 ± 3.83	27.27 ± 3.06	4.77%
Normal Zl treated	30.00 ± 1.78	31.00 ± 1.67	32.83 ± 1.83	4.59%
Diabetic Zl treated	29.00 ± 2.75	21.67 ± 2.94	24.50 ± 1.04	14.96%
Diabetic Glibenclamide (10 mg/kg)treated	30 ± 1.8	30.01 ± 1.7	29.3 ± 1.8	13.39%

Data represented as mean ± S.D. values of 6 animals each *p < 0.001, **p < 0.05 (One wayANOVA, Dunnet’s t-test, Graph pad prism software). Normal control was compared with extract treated normal groups. The diabetic control was compared with extract treated diabetic groups and standard

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