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Table 2 Anti-leishmanial (IC50 ±SD) and cytotoxic activity (CC50 ±SD) of essentials oils, some of their components and the positive controls

From: In vitro antileishmanial and cytotoxicity activities of essential oils from Haplophyllum tuberculatum A. Juss leaves, stems and aerial parts

 

Anti-leishmanial activity – promastigotes (L. mexicana mexicana)

Cytotoxicity -CHO

Selectivity index

Samples

IC50 (μg/ml) ± SD

CC50 (μg/ml) ± SD

CHO/Lmm

LEO 2013

16.69±0.35c

81.20±1.59d

4.86

SEO 2013

16.00±0.56c

49.64±8.56c

3.10

LSEO 2013

6.48±0.44b

27.79±3.73b

4.29

LEO 2015

19.44±1.00c

80.65±1.60d

4.15

SEO 2015

50.28±2.13d

82.56±5.51d

1.64

LSEO 2015

61.79±5.05e

79.06±0.80d

1.28

R- (+)-limonene

16.59±0.35c

29.65±0.78b

1.79

S- (-)-limonene

>100

75.89±0.88d

-

1-octanol

>100

>100

-

linalool

>100

>100

-

Amphotericin B

0.10±0.01a

nd

-

Camptothecin

nd

0.74±0.09a

-

  1. The letters (a–e) indicate significant differences between the samples according to the Duncan Test (p<0.05)