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Table 7 (A and B) Water intake (ml) of rats in the acute and sub-acute oral toxicity tests

From: Acute and sub-acute oral toxicity of Dracaena cinnabari resin methanol extract in rats

A

Acute oral toxicity

 

Sex

Control

DC 300 mg/kg

DC 2000 mg/kg

 

P value

 Week 1

F (n = 3)

102.56 ± 1.27

104.03 ± 1.78

104.34 ± 2.12

 

0.157

 Week 2

F (n = 3)

102.54 ± 0.97

104.00 ± 1.77

103.93 ± 2.01

 

0.199

B

Sub-acute oral toxicity

 

Sex

Control

DC 500 mg/kg

DC 1000 mg/kg

DC 1500 mg/kg

P value

 Week 1

M (n = 5)

123.18 ± 1.39

128.09 ± 2.34

128.03 ± 1.91

127.40 ± 2.11

0.000*

F (n = 5)

122.39 ± 0.42

125.51 ± 0.50

125.48 ± 0.37

125.46 ± 0.53

0.000*

 Week 2

M (n = 5)

124.06 ± 1.17

127.31 ± 1.50

127.44 ± 1.48

127.97 ± 1.85

0.000*

F (n = 5)

123.33 ± 0.55

125.68 ± 0.45

125.99 ± 0.41

125.87 ± 0.41

0.000*

 Week 3

M (n = 5)

125.23 ± 0.96

127.99 ± 1.33

127.98 ± 1.80

127.86 ± 1.69

0.004*

F (n = 5)

124.44 ± 0.49

127.29 ± 0.66

127.12 ± 0.61

127.16 ± 0.77

0.000*

 Week 4

M (n = 5)

125.89 ± 0.78

128.29 ± 1.95

128.54 ± 1.22

128.34 ± 1.61

0.007*

F (n = 5)

124.99 ± 0.50

127.28 ± 0.86

127.36 ± 0.63

127.56 ± 0.61

0.000*

  1. Values expressed as a mean ± standard deviation. Sex (male, M and female, F)
  2. *p-value less than 0.05, (p < 0.05) significant value. Numbers in bold indicate a statistically significant difference