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Table 1 (A and B) Percentage of body weight gain of rats in acute and sub-acute oral toxicity tests at each week

From: Acute and sub-acute oral toxicity of Dracaena cinnabari resin methanol extract in rats

A

Acute oral toxicity

 

Sex

Control

DC 300 mg/kg

DC 2000 mg/kg

 

P value

 0 day (g)

F (n = 3)

235.33 ± 5.03

250.00 ± 8.54

249.67 ± 9.61

 

 Week 1 (%)

F (n = 3)

5.82 ± 1.44

4.92 ± 1.62

4.15 ± 0.37

 

0.340

 Week 2 (%)

F (n = 3)

8.65 ± 1.96

8.53 ± 1.59

7.37 ± 1.17

 

0.586

B

Sub-acute oral toxicity

 
 

Sex

Control

DC 500 mg/kg

DC 1000 mg/kg

DC 1500 mg

P value

 0 day (g)

M (n = 5)

232.00 ± 4.70

223.40 ± 5.22

226.40 ± 5.13

229.80 ± 3.96

F (n = 5)

247.20 ± 6.14

233.40 ± 2.70

228.60 ± 8.02

232.20 ± 2.56

 Week 1 (%)

M (n = 5)

8.28 ± 0.91

8.56 ± 0.79

8.11 ± 1.15

8.61 ± 1.28

0.853

F (n = 5)

5.03 ± 2.44

4.71 ± 1.09

5.44 ± 1.71

5.50 ± 2.21

0.907

 Week 2 (%)

M (n = 5)

16.73 ± 1.03

16.37 ± 1.19

16.78 ± 0.83

16.09 ± 1.87

0.811

F (n = 5)

7.53 ± 3.21

7.62 ± 2.09

7.27 ± 2.59

8.49 ± 2.30

0.889

 Week 3 (%)

M (n = 5)

24.25 ± 2.13

24.17 ± 1.09

23.69 ± 1.64

23.48 ± 2.00

0.881

F (n = 5)

11.42 ± 2.77

10.44 ± 2.82

10.55 ± 2.64

12.30 ± 3.20

.0715

 Week 4 (%)

M (n = 5)

29.34 ± 2.70

28.55 ± 1.60

29.71 ± 2.08

29.75 ± 4.94

0.920

F (n = 5)

13.83 ± 2.76

13.18 ± 2.24

13.36 ± 3.05

15.23 ± 2.94

0.649

  1. Values expressed as a mean ± standard deviation. Sex (male, M and female, F)
  2. *p-value less than 0.05, (p < 0.05) significant value