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Table 1 Evaluation of the sub-chronic toxicity of NDAM in BALB/C mice

From: Subchronic toxicity, immunoregulation and anti-breast tumor effect of Nordamnacantal, an anthraquinone extracted from the stems of Morinda citrifolia L

 

Mortality

Body weight (g) Day 0

Body weight (g) Day 28

Body weight (g) Day 60

Toxic Signs

ALT (U/L)

AST (U/L)

ALP (U/L)

Control

None

20.30 ± 1.10

23.10 ± 1.70

25.60 ± 1.80

None

75.6 ± 34.0

301.5 ± 53.0

101.7 ± 13.0

LDNDAM

(10 mg/kg)

None

19.86 ± 1.30

23.85 ± 1.90

25.80 ± 1.70

None

69.4 ± 39.0

316.0 ± 37.0

125.4 ± 20.4

HDNDAM

(50 mg/kg)

None

20.80 ± 1.40

22.50 ± 2.10

24.90 ± 2.30

None

64.5 ± 32.0

246.0 ± 55.0

113.7 ± 19.0

  1. Parameters evaluated for sub-chronic toxicity test including mortality rates, body weight, toxic signs and biochemical analysis of ALT, AST and ALP
  2. No statistically significant was observed compared to control (p < 0.05)
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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