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Table 1 Evaluation of the sub-chronic toxicity of NDAM in BALB/C mice

From: Subchronic toxicity, immunoregulation and anti-breast tumor effect of Nordamnacantal, an anthraquinone extracted from the stems of Morinda citrifolia L

  Mortality Body weight (g) Day 0 Body weight (g) Day 28 Body weight (g) Day 60 Toxic Signs ALT (U/L) AST (U/L) ALP (U/L)
Control None 20.30 ± 1.10 23.10 ± 1.70 25.60 ± 1.80 None 75.6 ± 34.0 301.5 ± 53.0 101.7 ± 13.0
LDNDAM
(10 mg/kg)
None 19.86 ± 1.30 23.85 ± 1.90 25.80 ± 1.70 None 69.4 ± 39.0 316.0 ± 37.0 125.4 ± 20.4
HDNDAM
(50 mg/kg)
None 20.80 ± 1.40 22.50 ± 2.10 24.90 ± 2.30 None 64.5 ± 32.0 246.0 ± 55.0 113.7 ± 19.0
  1. Parameters evaluated for sub-chronic toxicity test including mortality rates, body weight, toxic signs and biochemical analysis of ALT, AST and ALP
  2. No statistically significant was observed compared to control (p < 0.05)