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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Protective and restorative effects of the traditional Chinese medicine Jitai tablet against methamphetamine-induced dopaminergic neurotoxicity

Fig. 2

Effect of Jitai tablet (JTT) on dopamine transporter (DAT) levels in the striatum as assayed by immunohistochemical staining (a) (Bar = 5.00 mm) and autoradiography with [99mTc]TRODAT-1 (b). Results of the two methods are accordant with each other. The remarkable reduction of DAT binding in the striatum induced by methamphetamine (METH) administration was significantly inhibited by JTT pre-treatment, or attenuated by post-treatment with high dose of JTT (JTT-H). Data are expressed as mean ± SD (n = 5). METH group vs. control group: # p < 0.05, ## p < 0.01; JTT treatment group vs METH group: * p < 0.05, ** p < 0.01

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