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Fig. 11 | BMC Complementary and Alternative Medicine

Fig. 11

From: Neoboutonia melleri var velutina Prain: in vitro and in vivo hepatoprotective effects of the aqueous stem bark extract on acute hepatitis models

Fig. 11

Histological changes in Concanavalin A-intoxicated mice. Animals were pretreated with either NVH extract or methylprednisolone during 3 consecutive days and acute liver injury was immediately induced with Concanavalin A intravenous injection after the last treatment. All animals were sacrificed 8 h after Concanavalin A injection. Liver sections were fixed and paraffin-embedded before haematoxylin-eosin staining. CTR: Control mice with normal liver structure; ConA: Concanavalin A treated mice with a damaged liver; ConA+NVH (15 and 75): Concanavalin A and extract treated mice with some persistent necrotic areas; ConA+MP: Concanavalin A and methylprednisolone treated mice without lesions. NVH: Neoboutonia velutina aqueous extract; MP: Methylprednisolone; ConA: Concanavalin A; CV: centrilobular vein; L: necrotic area. HEx100

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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