Fig. 10

Transaminases serum level in Concanavalin A-induced liver injury in mice. Animals were pretreated with either NVH extract or methylprednisolone during 3 consecutive days and acute liver injury was immediately induced with Concanavalin A intravenous injection after the last treatment. All animals were sacrificed 8 h after Concanavalin A injection. a: Dot plot showing Aspartate aminotransferase (left panel) and Alanine aminotransferase (right panel) serum level for each mouse in 5 different groups. Medians are indicated by a horizontal line. Significant Dunn’s post tests are indicated as *p < 0.05; **p < 0.01; ***p < 0.001; ns: non-significant. The p-value indicates the Mann-Whitney test. Two independent experiments were conducted; n ≥ 10 in each group. b: Correlation between Aspartate aminotransferase and Alanine aminotransferase level. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; NVH: Neoboutonia velutina aqueous extract; MP: Methylprednisolone, ConA: Concanavalin A