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Table 1 Minimal Inhibitory Concentration (MIC) in μg/mL of the crude MFS methanol extract, fractions and chloramphenicol

From: In vitro antibacterial and antibiotic modifying activity of crude extract, fractions and 3′,4′,7-trihydroxyflavone from Myristica fragrans Houtt against MDR Gram-negative enteric bacteria

Bacterial strains

Tested samples, MIC and MBC, and MIC in the presence of PAßN in parenthesis (μg/mL)

MFS

MFSa

MFSb

MFSc

MFSd

MFSe

CHL

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

MIC

MBC

R

E. coli

ATCC8739

32

512

16

256

1024

4

32

512

16

512

1024

2

1024

1024

4

16

4

ATCC10536

32

1024

32

256

32

512

16

512

512

4

128

32

AG100

64

1024

16

128

1024

8

64

1024

16

256

1024

4

512

8

64

8

AG100A

128(32)

1024

8

256

256

1

64

64

1

256

256

1

512

512

1

64(4)

AG102

32(< 8)

256

8

512

1024

2

32

512

16

128

1024

8

128

128

1

256

256

1

64(< 2)

256

4

AG100ATet

256(16)

128

1024

8

32

128

4

512

1024

2

512

1024

128(4)

MC4100

128

256

64

1024

16

512

512

512

8

64

8

W3110

32

256

8

256

64

512

1024

8

256

32

E. aerogenes

ATCC13048

512

256

128

1024

1024

8

64

8

EA-CM64

64(< 8)

128

512

4

64

512

8

512

1024

2

512

128(< 2)

EA3

256

1024

4

256

32

1024

32

512

1024

32

256

8

EA27

256(128)

128

1024

8

128

1024

8

256

1024

4

512

128(128)

EA289

512(16)

512

256

512

512

256(16)

EA294

64

512

8

128

1024

8

32

512

16

512

1024

8

128

16

EA298

256(64)

1024

4

256

64

1024

16

1024

1024

32(16)

64

2

K. pneumoniae

ATCC11296

256

1024

4

128

64

512

8

512

1024

2

1024

64

K2

1024

1024

1024

1

256

1024

4

1024

1024

32

128

4

K24

64

512

8

256

1024

4

128

1024

8

1024

1024

128

256

2

KP55

1024(512)

256

64

512

1024

2

512

64(32)

128

2

KP63

512(64)

512

1024

2

64(32)

256

4

P. stuartii

ATCC29916

256

512

2

32

1024

32

512

1024

2

512

128

ATCC299645

128

64

1024

16

512

1024

64

256

4

PS2636

128(16)

256

2

256

64

512

8

512

1024

2

1024

1024

1

128(8)

NEA16

128(16)

128

1024

8

32

1024

32

256

512

32(4)

256

8

E. cloacae

BM47

64(64)

1024

16

128

1024

8

32

128

4

512

1024

256(32)

BM67

128(128)

512

1024

64(32)

ECCI69

-(−)

512

1024

> 256(128)

256

P. aeruginosa

PA01

64

512

1024

1024

1024

1024

32

PA124

1024(1024)

256

256

1024

1024

256(4)

  1. R: CMB/CMI; −: values > 1024 for the extract and fractions, > 256 for chloramphenicol, or not calculated; (): values in parenthesis are MIC of substance in the presence of PAßN at 30 μg/mL; Values in Bold are the best MIC values for the crude MFS extract and its fractions