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Table 1 Minimal Inhibitory Concentration (MIC) in μg/mL of the crude MFS methanol extract, fractions and chloramphenicol

From: In vitro antibacterial and antibiotic modifying activity of crude extract, fractions and 3′,4′,7-trihydroxyflavone from Myristica fragrans Houtt against MDR Gram-negative enteric bacteria

Bacterial strains Tested samples, MIC and MBC, and MIC in the presence of PAßN in parenthesis (μg/mL)
MFS MFSa MFSb MFSc MFSd MFSe CHL
MIC MBC R MIC MBC R MIC MBC R MIC MBC R MIC MBC R MIC MBC R MIC MBC R
E. coli ATCC8739 32 512 16 256 1024 4 32 512 16 512 1024 2 1024 1024 4 16 4
ATCC10536 32 1024 32 256 32 512 16 512 512 4 128 32
AG100 64 1024 16 128 1024 8 64 1024 16 256 1024 4 512 8 64 8
AG100A 128(32) 1024 8 256 256 1 64 64 1 256 256 1 512 512 1 64(4)
AG102 32(< 8) 256 8 512 1024 2 32 512 16 128 1024 8 128 128 1 256 256 1 64(< 2) 256 4
AG100ATet 256(16) 128 1024 8 32 128 4 512 1024 2 512 1024 128(4)
MC4100 128 256 64 1024 16 512 512 512 8 64 8
W3110 32 256 8 256 64 512 1024 8 256 32
E. aerogenes ATCC13048 512 256 128 1024 1024 8 64 8
EA-CM64 64(< 8) 128 512 4 64 512 8 512 1024 2 512 128(< 2)
EA3 256 1024 4 256 32 1024 32 512 1024 32 256 8
EA27 256(128) 128 1024 8 128 1024 8 256 1024 4 512 128(128)
EA289 512(16) 512 256 512 512 256(16)
EA294 64 512 8 128 1024 8 32 512 16 512 1024 8 128 16
EA298 256(64) 1024 4 256 64 1024 16 1024 1024 32(16) 64 2
K. pneumoniae ATCC11296 256 1024 4 128 64 512 8 512 1024 2 1024 64
K2 1024 1024 1024 1 256 1024 4 1024 1024 32 128 4
K24 64 512 8 256 1024 4 128 1024 8 1024 1024 128 256 2
KP55 1024(512) 256 64 512 1024 2 512 64(32) 128 2
KP63 512(64) 512 1024 2 64(32) 256 4
P. stuartii ATCC29916 256 512 2 32 1024 32 512 1024 2 512 128
ATCC299645 128 64 1024 16 512 1024 64 256 4
PS2636 128(16) 256 2 256 64 512 8 512 1024 2 1024 1024 1 128(8)
NEA16 128(16) 128 1024 8 32 1024 32 256 512 32(4) 256 8
E. cloacae BM47 64(64) 1024 16 128 1024 8 32 128 4 512 1024 256(32)
BM67 128(128) 512 1024 64(32)
ECCI69 -(−) 512 1024 > 256(128) 256
P. aeruginosa PA01 64 512 1024 1024 1024 1024 32
PA124 1024(1024) 256 256 1024 1024 256(4)
  1. R: CMB/CMI; −: values > 1024 for the extract and fractions, > 256 for chloramphenicol, or not calculated; (): values in parenthesis are MIC of substance in the presence of PAßN at 30 μg/mL; Values in Bold are the best MIC values for the crude MFS extract and its fractions