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Table 1 Minimal Inhibitory Concentration (MIC) in μg/mL of the crude MFS methanol extract, fractions and chloramphenicol

From: In vitro antibacterial and antibiotic modifying activity of crude extract, fractions and 3′,4′,7-trihydroxyflavone from Myristica fragrans Houtt against MDR Gram-negative enteric bacteria

Bacterial strains Tested samples, MIC and MBC, and MIC in the presence of PAßN in parenthesis (μg/mL)
MFS MFSa MFSb MFSc MFSd MFSe CHL
MIC MBC R MIC MBC R MIC MBC R MIC MBC R MIC MBC R MIC MBC R MIC MBC R
E. coli ATCC8739 32 512 16 256 1024 4 32 512 16 512 1024 2 1024 – – 1024 – – 4 16 4
ATCC10536 32 1024 32 256 – – 32 512 16 512 – – 512 – – – – – 4 128 32
AG100 64 1024 16 128 1024 8 64 1024 16 256 1024 4 512 – – – – – 8 64 8
AG100A 128(32) 1024 8 256 256 1 64 64 1 256 256 1 512 512 1 – – – 64(4) – –
AG102 32(< 8) 256 8 512 1024 2 32 512 16 128 1024 8 128 128 1 256 256 1 64(< 2) 256 4
AG100ATet 256(16) – – 128 1024 8 32 128 4 512 1024 2 512 – – 1024 – – 128(4) – –
MC4100 128 – – 256 – – 64 1024 16 512 – – 512 – – 512 – – 8 64 8
W3110 32 256 8 256 – – 64 – – 512 – – 1024 – – – – – 8 256 32
E. aerogenes ATCC13048 512 – – 256 – – 128 – – 1024 – – 1024 – – – – – 8 64 8
EA-CM64 64(< 8) – – 128 512 4 64 512 8 512 1024 2 512 – – – – – 128(< 2) – –
EA3 256 1024 4 256 – – 32 1024 32 512 – – 1024 – – – – – 32 256 8
EA27 256(128) – – 128 1024 8 128 1024 8 256 1024 4 512 – – – – – 128(128) – –
EA289 512(16) – – 512 – – 256 – – 512 – – 512 – – – – – 256(16) – –
EA294 64 512 8 128 1024 8 32 512 16 512 – – 1024 – – – – – 8 128 16
EA298 256(64) 1024 4 256 – – 64 1024 16 1024 – – 1024 – – – – – 32(16) 64 2
K. pneumoniae ATCC11296 256 1024 4 128 – – 64 512 8 512 1024 2 1024 – – – – – 64 – –
K2 1024 – – 1024 1024 1 256 1024 4 1024 – – 1024 – – – – – 32 128 4
K24 64 512 8 256 1024 4 128 1024 8 1024 – – 1024 – – – – – 128 256 2
KP55 1024(512) – – 256 – – 64 – – 512 1024 2 512 – – – – – 64(32) 128 2
KP63 512(64) – – – – – 512 1024 2 – – – – – – – – – 64(32) 256 4
P. stuartii ATCC29916 – – – 256 512 2 32 1024 32 512 1024 2 512 – – – – – 128 – –
ATCC299645 – – – 128 – – 64 1024 16 512 – – 1024 – – – – – 64 256 4
PS2636 128(16) 256 2 256 – – 64 512 8 512 1024 2 1024 1024 1 – – – 128(8) – –
NEA16 128(16) – – 128 1024 8 32 1024 32 256 – – 512 – – – – – 32(4) 256 8
E. cloacae BM47 64(64) 1024 16 128 1024 8 32 128 4 512 – – 1024 – – – – – 256(32) – –
BM67 128(128) – – – – – 512 – – 1024 – – – – – – – – 64(32) – –
ECCI69 -(−) – – – – – 512 – – 1024 – – – – – – – – > 256(128) 256 –
P. aeruginosa PA01 64 – – 512 – – 1024 – – 1024 – – 1024 – – 1024 – – 32 – –
PA124 1024(1024) – – 256 – – 256 – – 1024 – – 1024 – – – – – 256(4) – –
  1. R: CMB/CMI; −: values > 1024 for the extract and fractions, > 256 for chloramphenicol, or not calculated; (): values in parenthesis are MIC of substance in the presence of PAßN at 30 μg/mL; Values in Bold are the best MIC values for the crude MFS extract and its fractions
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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