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Table 4 DNA damage [Mean ± SD]according to main individual characteristics of participants to the GIBIEX study [values at T0]

From: Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx]

Characteristics N IDN 5933 [TI%] N Placebo [TI%] p-value*
TI% T0 27 7.12 ± 4.72 20 8.30 ± 3.83  
      NS
TI% T1 27 6.03 ± 4.06 20 7.15 ± 4.43  
AgeTertiles
 65–77 y. 11 8.15 ± 6.51 6 7.33 ± 2.87 NS
 78–85 y. 8 6.23 ± 3.09 7 9.51 ± 4.83  
  ≥ 86 y. 8 6.59 ± 3.16 7 7.94 ± 3.67  
Sex
 Male 9 9.31 ± 4.78 9 7.06 ± 2.28 NS
 Female 18 6.03 ± 4.43 11 9.32 ± 4.60  
Marital Status
 Unmarried 8 7.92 ± 6.35 3 8.42 ± 5.23 NS
 Married 5 6.72 ± 3.82 4 5.66 ± 2.36  
 Divorced 1 6.07 ± 0  
 Widower 11 7.39 ± 4.61 11 9.63 ± 3.88  
Education
 No qualify/Elementary 13 8.52 ± 5.22 14 8.45 ± 4.01 NS
 Middle School 4 8.70 ± 4.06  
 High School/University 4 3.97 ± 1.60  
Smoking habit
 Never 13 6.91 ± 4.27 7 11.32 ± 3.79 NS
 Current Smoker 4 4.77 ± 1.36 3 6.35 ± 2.51  
 Ex-smoker 7 9.52 ± 6.52 5 8.36 ± 3.63  
 Not responding 3 5.57 ± 3.91 5 5.19 ± 0.99  
  1. *t-test quantitative [for unequal variances] or Chi square qualitative [NS: p > 0.05]. Row data are shown in Additional file 4
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