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Table 4 DNA damage [Mean ± SD]according to main individual characteristics of participants to the GIBIEX study [values at T0]

From: Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx]

Characteristics

N

IDN 5933 [TI%]

N

Placebo [TI%]

p-value*

TI% T0

27

7.12 ± 4.72

20

8.30 ± 3.83

 
     

NS

TI% T1

27

6.03 ± 4.06

20

7.15 ± 4.43

 

AgeTertiles

 65–77 y.

11

8.15 ± 6.51

6

7.33 ± 2.87

NS

 78–85 y.

8

6.23 ± 3.09

7

9.51 ± 4.83

 

  ≥ 86 y.

8

6.59 ± 3.16

7

7.94 ± 3.67

 

Sex

 Male

9

9.31 ± 4.78

9

7.06 ± 2.28

NS

 Female

18

6.03 ± 4.43

11

9.32 ± 4.60

 

Marital Status

 Unmarried

8

7.92 ± 6.35

3

8.42 ± 5.23

NS

 Married

5

6.72 ± 3.82

4

5.66 ± 2.36

 

 Divorced

1

6.07 ± 0

 

 Widower

11

7.39 ± 4.61

11

9.63 ± 3.88

 

Education

 No qualify/Elementary

13

8.52 ± 5.22

14

8.45 ± 4.01

NS

 Middle School

4

8.70 ± 4.06

 

 High School/University

4

3.97 ± 1.60

 

Smoking habit

 Never

13

6.91 ± 4.27

7

11.32 ± 3.79

NS

 Current Smoker

4

4.77 ± 1.36

3

6.35 ± 2.51

 

 Ex-smoker

7

9.52 ± 6.52

5

8.36 ± 3.63

 

 Not responding

3

5.57 ± 3.91

5

5.19 ± 0.99

 
  1. *t-test quantitative [for unequal variances] or Chi square qualitative [NS: p > 0.05]. Row data are shown in Additional file 4