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Table 3 Micronucleus frequency [Mean ± SD]according to main individual characteristics of participants to the GIBIEX study [values at T0]

From: Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx]

Characteristics N IDN 5933 [MN‰] N Placebo [MN‰] p-value*
MN‰ T0 27 10.00 ± 5.32 20 9.84 ± 4.95  
      NS
MN‰ T1 27 12.08 ± 6.11 20 12.68 ± 7.07  
AgeTertiles
 65–77 years 11 11.91 ± 6.75 6 8.10 ± 3.35 NS
 78–85 8 8.27 ± 3.11 7 10.84 ± 3.85  
  ≥ 86 8 9.10 ± 4.53 7 10.33 ± 6.99  
Sex
 Male 9 10.22 ± 4.55 9 8.73 ± 5.13 NS
 Female 18 9.89 ± 5.79 11 10.74 ± 4.84  
Marital Status
 Unmarried 8 8.97 ± 4.37 3 5.50 ± 2.02 NS
 Married 5 9.29 ± 3.25 4 8.81 ± 3.31  
 Divorced 1 6.11 ± −   
 Widower 11 11.44 ± 7.02 11 11.67 ± 5.57  
Education
 No degree/Elementary 13 11.61 ± 6.78 14 9.93 ± 5.37 NS
 Middle School 4 10.06 ± 4.75  
 High School/University 4 10.31 ± 3.85  
Smoking habit
 Never 13 9.28 ± 5.67 7 9.01 ± 3.56 NS
 Current Smoker 4 8.93 ± 5.52 3 8.25 ± 2.99  
 Ex-smoker 7 10.82 ± 4.86 5 11.44 ± 6.06  
 Not responding 3 12.59 ± 6.39 5 10.34 ± 7.05  
  1. *t-test quantitative [for unequal variances] or Chi square qualitative [NS: p > 0.05]. Row data are shown in Additional file 3
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