Antituberculosis activity, phytochemical identification of Costus speciosus (J. Koenig) Sm., Cymbopogon citratus (DC. Ex Nees) Stapf., and Tabernaemontana coronaria (L.) Willd. and their effects on the growth kinetics and cellular integrity of Mycobacterium tuberculosis H37Rv

Table 3 Effects of n-hexane plant partitions on the colony counts of Mycobacterium tuberculosis H37Rv over 7-day treatment period

Days	Control positive (no drug/extract)			Isoniazid (MIC: 0.078 μg/mL)			C. speciosus (MIC: 100 μg/mL)			C. citratus (MIC: 200 μg/mL)			T. coronaria (MIC: 100 μg/mL)
Days	Mean CFU/mL	Mean % of day 0	Mean % STDEV	Mean CFU/mL	Mean % of day 0	Mean % STDEV	Mean CFU/mL	Mean % of day 0	Mean % STDEV	Mean CFU/mL	Mean % of day 0	Mean % STDEV	Mean CFU/mL	Mean % of day 0	Mean % STDEV
0	1.36 _x 10⁶	100.00	0.87	1.29 _x 10⁶	100.00	4.56	1.86 _x 10⁶	100.00	0.32	9.00 _x 10⁶	100.00	5.24	4.92 _x 10⁶	100.00	7.19
1	1.48 _x 10⁶	108.59	5.59	1.04 _x 10⁶	80.65	1.13	8.08 _x 10⁵	43.60	4.37	3.58 _x 10⁶	39.81	9.87	8.42 _x 10⁵	17.12	4.20
2	2.27 _x 10⁶	166.87	4.16	1.80 _x 10⁵	13.87	9.87	7.25 _x 10⁵	39.10	8.13	1.13 _x 10⁶	12.59	6.24	6.17 _x 10⁵	12.54	4.59
3	2.50 _x 10⁶	184.05	0.00	1.58 _x 10⁵	12.26	4.47	1.35 _x 10⁵	7.28	5.24	9.42 _x 10⁵	10.46	1.25	5.08 _x 10⁵	10.34	11.59
4	2.71 _x 10⁶	199.39	2.18	9.92 _x 10⁴	7.68	5.94	1.07 _x 10⁵	5.75	8.84	8.75 _x 10⁵	9.72	6.73	8.08 _x 10⁴	1.64	1.46
5	3.58 _x 10⁶	263.80	3.29	7.92 _x 10⁴	6.13	1.49	1.67 _x 10²	0.01	0.00	5.92 _x 10⁵	6.57	5.98	7.83 _x 10⁴	1.59	6.02
6	4.50 _x 10⁶	331.29	5.24	6.58 _x 10⁴	5.10	5.37	1.67 _x 10²	0.01	0.00	5.92 _x 10⁵	6.57	1.99	4.25 _x 10⁴	0.86	2.77
7	3.08 _x 10⁶	226.99	3.82	3.67 _x 10⁴	2.84	12.86	1.67 _x 10²	0.01	0.00	3.83 _x 10⁵	4.26	0.00	4.25 _x 10⁴	0.86	2.77

Note: The mean CFU/mL was calculated from two sets of CFU/mL values in triplicate and the mean percentage of standard deviation (STDEV) was calculated based on the differences between two sets of percentage CFU/mL of Day 0

ISSN: 2662-7671