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Table 4 Effects of Withania Somnifera root extract on cell viability in the SH-SY5Y cells

From: The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells

 

Time of exposure

5 h

24 h

48 h

Vehicle

100.00 ± 3.64

100.00 ± 12.62

100.00 ± 15.10

0.10 mg/ml WSE

91.83 ± 14.38

90.52 ± 15.53

79.65 ± 14.40

0.25 mg/ml WSE

93.90 ± 5.40

72.63 ± 4.16

14.11 ± 1.43***

0.50 mg/ml WSE

107.21 ± 6.41

49.35 ± 3.79***

15.02 ± 4.13***

0.75 mg/ml WSE

107.04 ± 5.35

51.73 ± 2.69***

7.41 ± 3.02***

1.00 mg/ml WSE

109.90 ± 6.23

34.69 ± 6.29***

7.62 ± 2.76***

  1. Data are expressed as mean ± SEM (*** p < 0.001 vs vehicle are indicated in bold) and analyzed by two-way ANOVA. F-values reaching significance (p < 0.05) were further analysed by Bonferroni post-hoc test