TY - JOUR AU - Prasansuklab, Anchalee AU - Meemon, Krai AU - Sobhon, Prasert AU - Tencomnao, Tewin PY - 2017 DA - 2017/12/28 TI - Ethanolic extract of Streblus asper leaves protects against glutamate-induced toxicity in HT22 hippocampal neuronal cells and extends lifespan of Caenorhabditis elegans JO - BMC Complementary and Alternative Medicine SP - 551 VL - 17 IS - 1 AB - Although such local herb as Streblus asper (family Moraceae) has long been recognized for traditional folk medicines and important ingredient of traditional longevity formula, its anti-neurodegeneration or anti-aging activity is little known. This study aimed to investigate the neuroprotective effect of S. asper leaf extracts (SA-EE) against toxicity of glutamate-mediated oxidative stress, a crucial factor contributing to the neuronal loss in age-associated neurodegenerative diseases and the underlying mechanism as well as to evaluate its longevity effect. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-017-2050-3 DO - 10.1186/s12906-017-2050-3 ID - Prasansuklab2017 ER -