Skip to main content

Table 1 Demographic characteristics of AD patients at baseline visit

From: Adding Chinese herbal medicine to conventional therapy brings cognitive benefits to patients with Alzheimer’s disease: a retrospective analysis

  CT + H
(N = 243)
CT
(N = 101)
Total
(N = 344)
Male sex — n (%) 135 (55.55) 57 (56.43) 192 (55.81)
Age—yr., mean ± SD 69.61 ± 8.92 67.50 ± 10.65 68.99 ± 9.49
Education—yr., mean ± SD 11.05 ± 5.63* 9.60 ± 5.65 10.62 ± 5.66
MMSE score— mean ± SD 19.01 ± 6.37* 20.47 ± 5.07 19.44 ± 6.05
 Mild — n 121 56 177
 moderate — n 93 44 137
 severe — n 29 1 30
ADL score—mean ± SD 22.98 ± 9.13 21.28 ± 6.56 22.54 ± 8.56
BMI—kg/m2, mean ± SD 22.36 ± 3.79 22.73 ± 3.04 22.48 ± 3.57
Smoke — n (%) 37 (15.22) 10 (9.90) 47 (13.66)
Diabetes — n (%) 19 (7.81)** 0 (0) 19 (5.52)
Hypertension — n (%) 62 (25.51)*** 6 (5.94) 68 (19.76)
Donepezil — n (%) 202 (82.13)*** 98 (97.02) 300 (87.21)
Memantine — n (%) 64 (26.33)* 14 (13.86) 78 (22.67)
Both Donepezil and Memantine 58 (23.86)* 12 (11.88) 70 (20.34)
  1. CT + H, conventional therapy with herbal granule; CT, conventional therapy alone; MMSE, mini-mental state examination; ADL, activities of daily living; BMI, body mass index. The activities of daily living (ADL) contain 14 items, which cover 8 items of Lawton instrumental ADL scale and 6 items of Katz ADL scale (score 1–4), the range is 14 to 56, and higher scores indicate worse function. Some differences were observed in education, MMSE, diabetes history, hypertension history, donepezil use, memantine use and both donepezil and memantine
  2. * P < 0.05, ** <0.01, *** <0.001