Fig. 1

Ex vivo effects of PM21 (a 2:1 mixture of bamboo leaf extract and Japanese apricot fruit extract) on platelet aggregation. Six male rats in each experimental group were treated with test samples. PM21 was orally administered daily after overnight fasting for 3 days to three test groups at the doses of 75 mg/kg, 150 mg/kg, and 300 mg/kg, and aspirin was administered to positive control group at the dose of 50 mg/kg. Blood was collected 1 h after the final treatment. Platelet aggregation was induced by adding 5 μg/mL collagen and terminated after 5 min, and monitored by measuring light transmission with an aggregometer. Data show the mean ± SEM of six measurements. **p < 0.01, ***p < 0.001 versus vehicle control