Fig. 1

Effects of DJS on hippocampal estrogen synthesis in primary hippocampal cells and hippocampus of OVX mice. Rat primary hippocampal cells were treated with the DJS for 48 h. Female mice were administrated with DJS at the concentration of 50 and 100 mg/kg/day and EST at 200 μg/kg/day for 21 days after OVX surgery. Then, EST levels in the supernatant of cell culture (a) and hippocampus (b) were measured by ELISA. Values are means ± standard error. *p < 0.05 compared with the sham group, #p < 0.05 compared with the OVX group