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Table 2 Percent anticholinesterase activity of various samples of N. micrantha

From: Anticholinesterase and antioxidant potentials of Nonea micrantha Bioss. & Reut along with GC-MS analysis

Sample Concentration (μg/mL) %AChE inhibition (mean ± SEM) AChE IC50(μg/mL) %BChE inhibition (mean ± SEM) BChE IC50(μg/mL)
Nm.Cr 1000 54.32 ± 0.67*** 340 75.31 ± 0.56*** 44
500 51.81 ± 0.52*** 68.73 ± 0.43***
250 48.39 ± 0.59*** 64.42 ± 0.76***
125 43.61 ± 0.32*** 59.57 ± 0.38***
Nm.Hex 1000 75.51 ± 0.73*** 44 67.82 ± 0.34*** 400
500 69.67 ± 0.51*** 53.44 ± 0.73***
250 64.35 ± 0.47*** 39.53 ± 0.51***
125 58.66 ± 0.61*** 30.67 ± 0.58***
Nm.Cf 1000 63.48 ± 0.59*** 144 53.76 ± 0.34*** 750
500 58.29 ± 0.83*** 45.24 ± 0.61***
250 53.54 ± 0.52*** 37.57 ± 0.83***
125 49.64 ± 0.44*** 26.39 ± 0.42***
Nm.EtAc 1000 68.54 ± 0.59*** 100 54.71 ± 0.89*** 720
500 63.72 ± 0.34*** 47.54 ± 0.44***
250 57.39 ± 0.78*** 33.28 ± 0.76***
125 51.67 ± 0.63*** 28.54 ± 1.22***
Nm.Aq 1000 59.67 ± 0.57*** 350 81.49 ± 0.89*** 110
500 53.72 ± 0.63*** 76.52 ± 1.03***
250 46.34 ± 0.69*** 58.39 ± 0.58***
125 41.58 ± 0.73*** 53.47 ± 0.52***
Nm.Sp 1000 47.56 ± 0.57*** 1035 83.49 ± 0.27*** 90
500 44.31 ± 0.29*** 71.52 ± 0.83***
250 38.73 ± 0.68*** 66.41 ± 0.58***
125 31.59 ± 0.43*** 53.73 ± 0.41***
Galantamine 1000 94.22 ± 1.01 < 0.1 96.00 ± 0.30 < 0.1
500 92.28 ± 0.43 92.90 ± 0.60
250 85.35 ± 0.83 89.45 ± 0.90
125 83.05 ± 1.02 86.23 ± 0.22
  1. Data is represented as mean ± SEM; n = 3. Values significantly different as compared to standared drug (Galanthamine) i.e. *: 0.05, **: 0.01 and ***: 0.001 at 90% confidence interval