Sample | Concentration (μg/mL) | %AChE inhibition (mean ± SEM) | AChE IC50(μg/mL) | %BChE inhibition (mean ± SEM) | BChE IC50(μg/mL) |
---|---|---|---|---|---|
Nm.Cr | 1000 | 54.32 ± 0.67*** | 340 | 75.31 ± 0.56*** | 44 |
500 | 51.81 ± 0.52*** | 68.73 ± 0.43*** | |||
250 | 48.39 ± 0.59*** | 64.42 ± 0.76*** | |||
125 | 43.61 ± 0.32*** | 59.57 ± 0.38*** | |||
Nm.Hex | 1000 | 75.51 ± 0.73*** | 44 | 67.82 ± 0.34*** | 400 |
500 | 69.67 ± 0.51*** | 53.44 ± 0.73*** | |||
250 | 64.35 ± 0.47*** | 39.53 ± 0.51*** | |||
125 | 58.66 ± 0.61*** | 30.67 ± 0.58*** | |||
Nm.Cf | 1000 | 63.48 ± 0.59*** | 144 | 53.76 ± 0.34*** | 750 |
500 | 58.29 ± 0.83*** | 45.24 ± 0.61*** | |||
250 | 53.54 ± 0.52*** | 37.57 ± 0.83*** | |||
125 | 49.64 ± 0.44*** | 26.39 ± 0.42*** | |||
Nm.EtAc | 1000 | 68.54 ± 0.59*** | 100 | 54.71 ± 0.89*** | 720 |
500 | 63.72 ± 0.34*** | 47.54 ± 0.44*** | |||
250 | 57.39 ± 0.78*** | 33.28 ± 0.76*** | |||
125 | 51.67 ± 0.63*** | 28.54 ± 1.22*** | |||
Nm.Aq | 1000 | 59.67 ± 0.57*** | 350 | 81.49 ± 0.89*** | 110 |
500 | 53.72 ± 0.63*** | 76.52 ± 1.03*** | |||
250 | 46.34 ± 0.69*** | 58.39 ± 0.58*** | |||
125 | 41.58 ± 0.73*** | 53.47 ± 0.52*** | |||
Nm.Sp | 1000 | 47.56 ± 0.57*** | 1035 | 83.49 ± 0.27*** | 90 |
500 | 44.31 ± 0.29*** | 71.52 ± 0.83*** | |||
250 | 38.73 ± 0.68*** | 66.41 ± 0.58*** | |||
125 | 31.59 ± 0.43*** | 53.73 ± 0.41*** | |||
Galantamine | 1000 | 94.22 ± 1.01 | < 0.1 | 96.00 ± 0.30 | < 0.1 |
500 | 92.28 ± 0.43 | 92.90 ± 0.60 | |||
250 | 85.35 ± 0.83 | 89.45 ± 0.90 | |||
125 | 83.05 ± 1.02 | 86.23 ± 0.22 |