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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Blockade of nicotine sensitization by methanol extracts of Glycyrrhizae radix mediated via antagonism of accumbal oxidative stress

Fig. 5

Effects of intra-NaccSh infusion of t-BOOH on the anti-sensitization action of MEGR. Sixty minutes after the 4th MEGR, rats received bilateral infusions of t-BOOH into the NaccSh, were systemically challenged with nicotine, and then tested in the locomotor testing boxes for 60 min. All data are expressed as means ± SEM (n = 4–5). Nic: nicotine, S: saline, MRS: modified Ringers’ solution, MEGR: methanol extract of G. radix, MEGR180: 180 mg/kg/day MEGR once a day for 4 consecutive days. ## P < 0.01versus S/DW/MRS/S group; $ P < 0.05 versus Nic/DW/MRS/Nic group; & P < 0.05 versus Nic/MEGR60/t-BooH/Nic group (one-way ANOVA followed by Newman-Keuls post-hoc test)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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