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Table 4 Effect of MMMC on the PGE2 content in ethanol-induced gastric tissue of rats

From: Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats

Pre-treatment Ratio Dose (mg/kg) PGE2 (pg/mL)
Normal   188.10 ± 1.70
2% Tween 80   159.20 ± 0.93*
Ranitidine   100 186.40 ± 4.93***
MMMC 1:1 15 174.30 ± 2.65
150 188.40 ± 4.40***
300 193.40 ± 5.98***
1:3 15 173.40 ± 3.93
150 183.40 ± 3.43***
300 192.40 ± 4.72***
3:1 15 162.30 ± 5.79
150 172.20 ± 2.73
300 185.20 ± 3.34***
  1. Data are presented as mean ± S.E.M. Sixty rats (n = 6 in each group) were used in this study. Statistical analysis was performed using the one-way ANOVA followed by Dunnet’s multiple comparison tests. *P < 0.05,**P < 0.01 and ***P < 0.001 as compared to ulcer control group