|
Pre-treatment
|
Ratio
|
Dose (mg/kg)
|
Volume of gastric juice (ml)
|
pH
|
Total acidity (mEq/L)
|
|---|
|
2% Tween 80
| |
–
|
4.58 ± 0.375
|
1.57 ± 0.428
|
664.0 ± 31.79
|
|
Ranitidine
| |
100
|
3.25 ± 0.250*
|
4.13 ± 0.632***
|
386.7 ± 24.59***
|
|
MMMC
|
1:1
|
15
|
2.58 ± 0.301***
|
1.98 ± 0.319
|
600.0 ± 61.97
|
|
150
|
2.50 ± 0.183***
|
2.32 ± 0.111*
|
710.0 ± 35.68
|
|
300
|
2.08 ± 0.352***
|
2.38 ± 0.120*
|
466.7 ± 24.59**
|
|
1:3
|
15
|
2.17 ± 0.211***
|
1.38 ± 0.294
|
540.0 ± 58.20
|
|
150
|
2.17 ± 0.279***
|
1.90 ± 0.608
|
370.0 ± 15.28***
|
|
300
|
2.58 ± 0.375***
|
2.03 ± 0.328
|
266.7 ± 19.78***
|
|
3:1
|
15
|
4.08 ± 0.271
|
1.77 ± 0.163
|
633.3 ± 31.69
|
|
150
|
2.75 ± 0.214***
|
3.85 ± 0.264***
|
306.7 ± 30.40***
|
|
300
|
1.83 ± 0.247***
|
1.92 ± 0.409
|
590.0 ± 45.46
|
- Values are expressed as mean ± SEM for six animals in each group. One way ANOVA was followed by Dunnett’s post hoc test
- *p < 0.05 as compared to the control group within the respective column
- **p < 0.01 as compared to the control group within the respective column
- ***p < 0.001 as compared to the control group within the respective column
