Intervention vs control | Overall analysis or subgroup analysis | Subgroup details | Outcome measure | Number of studies | References | Number of participants | Results | I2 |
---|---|---|---|---|---|---|---|---|
YPFS vs Pharmacotherapy | Overall | N/A | Effective rate | 8 | 833 | RR1.07, 95%CI [0.94, 1.22] | 70% | |
YPFS vs Pharmacotherapy | Subgroup analysis (Pharmacotherapy) | Second-generation antihistamines | Effective rate | 7 | 613 | RR1.04, 95%CI [0.90, 1.19] | 64% | |
YPFS vs Pharmacotherapy | Subgroup analysis (treatment duration) | Two weeks | Effective rate | 5 | 410 | RR1.04, 95%CI [0.92, 1.18] | 6% | |
YPFS vs Pharmacotherapy | Subgroup analysis (treatment duration) | Three weeks or more | Effective rate | 3 | 423 | RR1.08, 95%CI [0.82, 1.42] | 90% | |
YPFS plus pharmacotherapy versus pharmacotherapy | Overall | Second-generation antihistamines | Itchy nose | 4 | 418 | MD-0.46, 95%CI [−0.50, −0.42]* | 0 | |
YPFS plus pharmacotherapy versus pharmacotherapy | Overall | Second-generation antihistamines | Sneezing | 4 | 418 | MD-0.41, 95%CI [−0.47, −0.35]* | 54% | |
YPFS plus pharmacotherapy versus pharmacotherapy | Overall | Second-generation antihistamines | Blocked nose | 4 | 418 | MD-0.46, 95%CI [−0.54, −0.39]* | 60% | |
YPFS plus pharmacotherapy versus pharmacotherapy | Overall | Second-generation antihistamines | Runny nose | 3 | 318 | MD-0.42, 95%CI [−0.58, −0.26]* | 70% | |
YPFS plus pharmacotherapy versus pharmacotherapy | Overall | N/A | Effective rate | 12 | 1077 | RR1.27, 95%CI [1.19, 1.34]* | 22% | |
YPFS plus pharmacotherapy versus pharmacotherapy | Subgroup analysis (Pharmacotherapy) | Second-generation antihistamines | Effective rate | 8 | 727 | RR1.28, 95%CI [1.19, 1.37]* | 43% | |
YPFS plus pharmacotherapy versus pharmacotherapy | Subgroup analysis (Pharmacotherapy) | Second-generation antihistamine + intranasal glucocorticosteroids | Effective rate | 2 | 225 | RR1.29, 95%CI [1.14,1.46]* | 0 | |
YPFS plus pharmacotherapy versus pharmacotherapy | Subgroup analysis (Pharmacotherapy) | Intranasal glucocorticosteroids | Effective rate | 2 | 125 | RR1.15, 95%CI [0.97, 1.36] | 0 | |
YPFS plus pharmacotherapy versus pharmacotherapy | Subgroup analysis (treatment duration) | Two weeks | Effective rate | 4 | 353 | RR1.13, 95%CI [0.84, 1.54] | 88% | |
YPFS plus pharmacotherapy versus pharmacotherapy | Subgroup analysis (treatment duration) | Three weeks or more | Effective rate | 8 | 725 | RR1.15, 95%CI [1.01,1.32]* | 74% |