YPFS vs Pharmacotherapy
|
Overall
|
N/A
|
Effective rate
|
8
|
[16,17,18,19,20,21,22,23]
|
833
|
RR1.07, 95%CI [0.94, 1.22]
|
70%
|
YPFS vs Pharmacotherapy
|
Subgroup analysis (Pharmacotherapy)
|
Second-generation antihistamines
|
Effective rate
|
7
|
[17,18,19,20,21,22,23]
|
613
|
RR1.04, 95%CI [0.90, 1.19]
|
64%
|
YPFS vs Pharmacotherapy
|
Subgroup analysis (treatment duration)
|
Two weeks
|
Effective rate
|
5
|
[17, 19,20,21, 23]
|
410
|
RR1.04, 95%CI [0.92, 1.18]
|
6%
|
YPFS vs Pharmacotherapy
|
Subgroup analysis (treatment duration)
|
Three weeks or more
|
Effective rate
|
3
|
[16, 18, 22]
|
423
|
RR1.08, 95%CI [0.82, 1.42]
|
90%
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Overall
|
Second-generation antihistamines
|
Itchy nose
|
4
|
[29, 32, 34, 35]
|
418
|
MD-0.46, 95%CI [−0.50, −0.42]*
|
0
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Overall
|
Second-generation antihistamines
|
Sneezing
|
4
|
[29, 32, 34, 35]
|
418
|
MD-0.41, 95%CI [−0.47, −0.35]*
|
54%
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Overall
|
Second-generation antihistamines
|
Blocked nose
|
4
|
[29, 32, 34, 35]
|
418
|
MD-0.46, 95%CI [−0.54, −0.39]*
|
60%
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Overall
|
Second-generation antihistamines
|
Runny nose
|
3
|
[29, 32, 35]
|
318
|
MD-0.42, 95%CI [−0.58, −0.26]*
|
70%
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Overall
|
N/A
|
Effective rate
|
12
|
[23,24,25,26,27,28,29,30,31,32, 34, 35]
|
1077
|
RR1.27, 95%CI [1.19, 1.34]*
|
22%
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Subgroup analysis (Pharmacotherapy)
|
Second-generation antihistamines
|
Effective rate
|
8
|
[23, 24, 28,29,30, 32, 34, 35]
|
727
|
RR1.28, 95%CI [1.19, 1.37]*
|
43%
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Subgroup analysis (Pharmacotherapy)
|
Second-generation antihistamine + intranasal glucocorticosteroids
|
Effective rate
|
2
|
[25, 27]
|
225
|
RR1.29, 95%CI [1.14,1.46]*
|
0
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Subgroup analysis (Pharmacotherapy)
|
Intranasal glucocorticosteroids
|
Effective rate
|
2
|
[26, 31]
|
125
|
RR1.15, 95%CI [0.97, 1.36]
|
0
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Subgroup analysis (treatment duration)
|
Two weeks
|
Effective rate
|
4
|
[23, 25, 31, 34]
|
353
|
RR1.13, 95%CI [0.84, 1.54]
|
88%
|
YPFS plus pharmacotherapy versus pharmacotherapy
|
Subgroup analysis (treatment duration)
|
Three weeks or more
|
Effective rate
|
8
|
[24, 26,27,28,29,30, 32, 35]
|
725
|
RR1.15, 95%CI [1.01,1.32]*
|
74%
|