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Table 3 Summary of meta-analyses results

From: Potential effectiveness of Chinese herbal medicine Yu ping feng san for adult allergic rhinitis: a systematic review and meta-analysis of randomized controlled trials

Intervention vs control

Overall analysis or subgroup analysis

Subgroup details

Outcome measure

Number of studies

References

Number of participants

Results

I2

YPFS vs Pharmacotherapy

Overall

N/A

Effective rate

8

[16,17,18,19,20,21,22,23]

833

RR1.07, 95%CI [0.94, 1.22]

70%

YPFS vs Pharmacotherapy

Subgroup analysis (Pharmacotherapy)

Second-generation antihistamines

Effective rate

7

[17,18,19,20,21,22,23]

613

RR1.04, 95%CI [0.90, 1.19]

64%

YPFS vs Pharmacotherapy

Subgroup analysis (treatment duration)

Two weeks

Effective rate

5

[17, 19,20,21, 23]

410

RR1.04, 95%CI [0.92, 1.18]

6%

YPFS vs Pharmacotherapy

Subgroup analysis (treatment duration)

Three weeks or more

Effective rate

3

[16, 18, 22]

423

RR1.08, 95%CI [0.82, 1.42]

90%

YPFS plus pharmacotherapy versus pharmacotherapy

Overall

Second-generation antihistamines

Itchy nose

4

[29, 32, 34, 35]

418

MD-0.46, 95%CI [−0.50, −0.42]*

0

YPFS plus pharmacotherapy versus pharmacotherapy

Overall

Second-generation antihistamines

Sneezing

4

[29, 32, 34, 35]

418

MD-0.41, 95%CI [−0.47, −0.35]*

54%

YPFS plus pharmacotherapy versus pharmacotherapy

Overall

Second-generation antihistamines

Blocked nose

4

[29, 32, 34, 35]

418

MD-0.46, 95%CI [−0.54, −0.39]*

60%

YPFS plus pharmacotherapy versus pharmacotherapy

Overall

Second-generation antihistamines

Runny nose

3

[29, 32, 35]

318

MD-0.42, 95%CI [−0.58, −0.26]*

70%

YPFS plus pharmacotherapy versus pharmacotherapy

Overall

N/A

Effective rate

12

[23,24,25,26,27,28,29,30,31,32, 34, 35]

1077

RR1.27, 95%CI [1.19, 1.34]*

22%

YPFS plus pharmacotherapy versus pharmacotherapy

Subgroup analysis (Pharmacotherapy)

Second-generation antihistamines

Effective rate

8

[23, 24, 28,29,30, 32, 34, 35]

727

RR1.28, 95%CI [1.19, 1.37]*

43%

YPFS plus pharmacotherapy versus pharmacotherapy

Subgroup analysis (Pharmacotherapy)

Second-generation antihistamine + intranasal glucocorticosteroids

Effective rate

2

[25, 27]

225

RR1.29, 95%CI [1.14,1.46]*

0

YPFS plus pharmacotherapy versus pharmacotherapy

Subgroup analysis (Pharmacotherapy)

Intranasal glucocorticosteroids

Effective rate

2

[26, 31]

125

RR1.15, 95%CI [0.97, 1.36]

0

YPFS plus pharmacotherapy versus pharmacotherapy

Subgroup analysis (treatment duration)

Two weeks

Effective rate

4

[23, 25, 31, 34]

353

RR1.13, 95%CI [0.84, 1.54]

88%

YPFS plus pharmacotherapy versus pharmacotherapy

Subgroup analysis (treatment duration)

Three weeks or more

Effective rate

8

[24, 26,27,28,29,30, 32, 35]

725

RR1.15, 95%CI [1.01,1.32]*

74%

  1. Note: YPFS: yu ping feng san; RR: risk ratio; MD: mean difference; CI: Confidence interval. *: significant difference between two groups was detected