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Table 3 Summary of meta-analyses results

From: Potential effectiveness of Chinese herbal medicine Yu ping feng san for adult allergic rhinitis: a systematic review and meta-analysis of randomized controlled trials

Intervention vs control Overall analysis or subgroup analysis Subgroup details Outcome measure Number of studies References Number of participants Results I2
YPFS vs Pharmacotherapy Overall N/A Effective rate 8 [16,17,18,19,20,21,22,23] 833 RR1.07, 95%CI [0.94, 1.22] 70%
YPFS vs Pharmacotherapy Subgroup analysis (Pharmacotherapy) Second-generation antihistamines Effective rate 7 [17,18,19,20,21,22,23] 613 RR1.04, 95%CI [0.90, 1.19] 64%
YPFS vs Pharmacotherapy Subgroup analysis (treatment duration) Two weeks Effective rate 5 [17, 19,20,21, 23] 410 RR1.04, 95%CI [0.92, 1.18] 6%
YPFS vs Pharmacotherapy Subgroup analysis (treatment duration) Three weeks or more Effective rate 3 [16, 18, 22] 423 RR1.08, 95%CI [0.82, 1.42] 90%
YPFS plus pharmacotherapy versus pharmacotherapy Overall Second-generation antihistamines Itchy nose 4 [29, 32, 34, 35] 418 MD-0.46, 95%CI [−0.50, −0.42]* 0
YPFS plus pharmacotherapy versus pharmacotherapy Overall Second-generation antihistamines Sneezing 4 [29, 32, 34, 35] 418 MD-0.41, 95%CI [−0.47, −0.35]* 54%
YPFS plus pharmacotherapy versus pharmacotherapy Overall Second-generation antihistamines Blocked nose 4 [29, 32, 34, 35] 418 MD-0.46, 95%CI [−0.54, −0.39]* 60%
YPFS plus pharmacotherapy versus pharmacotherapy Overall Second-generation antihistamines Runny nose 3 [29, 32, 35] 318 MD-0.42, 95%CI [−0.58, −0.26]* 70%
YPFS plus pharmacotherapy versus pharmacotherapy Overall N/A Effective rate 12 [23,24,25,26,27,28,29,30,31,32, 34, 35] 1077 RR1.27, 95%CI [1.19, 1.34]* 22%
YPFS plus pharmacotherapy versus pharmacotherapy Subgroup analysis (Pharmacotherapy) Second-generation antihistamines Effective rate 8 [23, 24, 28,29,30, 32, 34, 35] 727 RR1.28, 95%CI [1.19, 1.37]* 43%
YPFS plus pharmacotherapy versus pharmacotherapy Subgroup analysis (Pharmacotherapy) Second-generation antihistamine + intranasal glucocorticosteroids Effective rate 2 [25, 27] 225 RR1.29, 95%CI [1.14,1.46]* 0
YPFS plus pharmacotherapy versus pharmacotherapy Subgroup analysis (Pharmacotherapy) Intranasal glucocorticosteroids Effective rate 2 [26, 31] 125 RR1.15, 95%CI [0.97, 1.36] 0
YPFS plus pharmacotherapy versus pharmacotherapy Subgroup analysis (treatment duration) Two weeks Effective rate 4 [23, 25, 31, 34] 353 RR1.13, 95%CI [0.84, 1.54] 88%
YPFS plus pharmacotherapy versus pharmacotherapy Subgroup analysis (treatment duration) Three weeks or more Effective rate 8 [24, 26,27,28,29,30, 32, 35] 725 RR1.15, 95%CI [1.01,1.32]* 74%
  1. Note: YPFS: yu ping feng san; RR: risk ratio; MD: mean difference; CI: Confidence interval. *: significant difference between two groups was detected