TY - JOUR AU - Bajgai, Johny AU - Fadriquela, Ailyn AU - Ara, Jesmin AU - Begum, Rahima AU - Ahmed, Md Faruk AU - Kim, Cheol-Su AU - Kim, Soo-Ki AU - Shim, Kwang-Yong AU - Lee, Kyu-Jae PY - 2017 DA - 2017/10/13 TI - Balneotherapeutic effects of high mineral spring water on the atopic dermatitis-like inflammation in hairless mice via immunomodulation and redox balance JO - BMC Complementary and Alternative Medicine SP - 481 VL - 17 IS - 1 AB - Atopic dermatitis (AD) is a chronic relapsing allergic inflammatory skin disease that currently affects millions of children and adults worldwide. Drugs used to treat these inflammatory diseases include anti-histamines, corticosteroids and calcineurin inhibitors but these drugs have their limitations such as adverse effects with their long-term usage. Thus, researcher’s interest in several alternative and complementary therapies are continually growing and balneotherapy is one of these approaches. Therefore, we investigate the bathing effect of high concentration mineral spring water (HMW) on redox balance and immune modulation in 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis like inflammation in hairless mice. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-017-1985-8 DO - 10.1186/s12906-017-1985-8 ID - Bajgai2017 ER -