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Table 4 Morphometric analysis of the sciatic nerve at the end of the 8th week

From: Protective effects of methanolic extract of Juglans regia L. leaf on streptozotocin-induced diabetic peripheral neuropathy in rats

Experimental Groups

Axon density (N/mm2)

Fiber area (μm2)

G ratio (axon diameter/fiber diameter)

Vehicle

27.67 ± 8.59

6563 ± 2366

0.37 ± 0.05

STZ

34.40 ± 18.00

4703 ± 1651*

0.44 ± 0.07*

Preventive

38.53 ± 8.79

5716 ± 1868***

0.35 ± 0.06**

Curative

32.80 ± 7.62

6012 ± 2323**

0.36 ± 0.08**

GRL

28.67 ± 8.59

6463 ± 2360

0.38 ± 0.05

  1. Data are represented in Mean ± SD of 7 rats/group
  2. * p < 0.001 versus vehicle and GRL group
  3. ** p < 0.001 versus STZ group
  4. *** p < 0.05 versus STZ group by one-way ANOVA followed by Tukey′s post-hoc tests