| Change in paw volume (ml) and percent inhibition (%) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Group | 0Â h | 1Â h | % | 2Â h | % | 3Â h | % | 4Â h | % | 5Â h | % |
DW | 0.43 ± 0.01 | 0.56 ± 0.01 | – | 0.71 ± 0.01 | – | 0.73 ± 0.01 |  | 0.80 ± 0.01 | – | 0.88 ± 0.02 | – |
ASA | 0.42 ± 0.01 | 0.51 ± 0.02 | 35.6 | 0.53 ± 0.01a3c1 | 62.8 | 0.58 ± 0.02a3 | 48.1 | 0.64 ± 0.01a3 | 42.4 | 0.67 ± 0.01a3 | 45.8 |
AF 100 | 0.46 ± 0.02 | 0.55 ± 0.02 | 30.3 | 0.59 ± 0.01a3e1 | 52.1 | 0.62 ± 0.01a3e1 | 47.4 | 0.66 ± 0.02a3 | 45.6 | 0.72 ± 0.02a3e1 | 42.0 |
AF 200 | 0.44 ± 0.02 | 0.52 ± 0.01 | 34.8 | 0.55 ± 0.01a3 | 59.9 | 0.59 ± 0.01a3 | 51.3 | 0.63 ± 0.01a3 | 48.8 | 0.68 ± 0.01a3 | 46.9 |
AF 400 | 0.43 ± 0.02 | 0.50 ± 0.01c1 | 47.0 | 0.53 ± 0.01a3c1 | 67.0 | 0.56 ± 0.02a3c1 | 60.1 | 0.60 ± 0.02a3b1 | 54.9 | 0.65 ± 0.01a3c1d1 | 51.8 |