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Table 6 Effect of the aqueous fraction of Moringa stenopetala on carrageenan- induced paw model and percent inhibition from increase in paw volume

From: Anti-inflammatory and analgesic activities of solvent fractions of the leaves of Moringa stenopetala Bak. (Moringaceae) in mice models

 

Change in paw volume (ml) and percent inhibition (%)

Group

0 h

1 h

%

2 h

%

3 h

%

4 h

%

5 h

%

DW

0.43 ± 0.01

0.56 ± 0.01

–

0.71 ± 0.01

–

0.73 ± 0.01

 

0.80 ± 0.01

–

0.88 ± 0.02

–

ASA

0.42 ± 0.01

0.51 ± 0.02

35.6

0.53 ± 0.01a3c1

62.8

0.58 ± 0.02a3

48.1

0.64 ± 0.01a3

42.4

0.67 ± 0.01a3

45.8

AF 100

0.46 ± 0.02

0.55 ± 0.02

30.3

0.59 ± 0.01a3e1

52.1

0.62 ± 0.01a3e1

47.4

0.66 ± 0.02a3

45.6

0.72 ± 0.02a3e1

42.0

AF 200

0.44 ± 0.02

0.52 ± 0.01

34.8

0.55 ± 0.01a3

59.9

0.59 ± 0.01a3

51.3

0.63 ± 0.01a3

48.8

0.68 ± 0.01a3

46.9

AF 400

0.43 ± 0.02

0.50 ± 0.01c1

47.0

0.53 ± 0.01a3c1

67.0

0.56 ± 0.02a3c1

60.1

0.60 ± 0.02a3b1

54.9

0.65 ± 0.01a3c1d1

51.8

  1. Values are expressed as Mean ± S.E.M (n = 6); aagainst the control, bagainst the standard drug, cagainst AF100, dagainst AF200, eagainst AF400, 1 P < 0.05, 2 P < 0.01, 3 P < 0.001; DW distilled water, ASA aspirin, AF refers to aqueous fraction of Moringa stenopetala