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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Electroacupuncture ameliorating post-stroke cognitive impairments via inhibition of peri-infarct astroglial and microglial/macrophage P2 purinoceptors-mediated neuroinflammation and hyperplasia

Fig. 4

Effects of EA on astroglial and microglial/macrophage hyperplasia after MCAO/R injury. a, c Immunohistochemistry of ED1-positive and GFAP-positive cells in peri-infract hippocampal CA1 and sensorimotor cortex of each groups at Day 7 after EA treatment (brown cells, Scale bar = 20 μm). b, d Quantification of microglial/macrophage and astroglial positive cells showed lower density in the MCAO/R + EA group compared to the MCAO/R group and the MCAO/R+ Non-EA group. ED1-positive and GFAP-positive IOD in regions (0.3 × 0.2 mm2) were counted. Data are shown as mean ± S.E.M from 6 individual rats in each group. && P < 0.01, the MCAO/R group versus the Sham group; **P < 0.01, *P < 0.05, the MCAO/R + EA group versus the MCAO/R group; ## P < 0.01, # P < 0.05, the MCAO/R + EA group versus the MCAO/R+ Non-EA group

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