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Table 7 Hematological data for female rats treated with JDHY granules for 13 weeks of treatment

From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats

Dose (g/kg/d)

0

80

100

130

Females

 WBC(109/L)

7.91 ± 1.89a

8.94 ± 1.25

7.44 ± 2.08

8.37 ± 2.10

 LYM(109/L)

3.42 ± 1.29

4.05 ± 0.97

3.58 ± 1.36

4.11 ± 1.44

 LYM%(%)

46.59 ± 13.74

46.04 ± 11.71

47.17 ± 12.50

47.89 ± 11.92

 RC(%)

16.40 ± 2.06

16.30 ± 2.11

16.80 ± 2.34

16.90 ± 2.07

 MID(109/L)

1.31 ± 0.61

1.27 ± 0.313

1.12 ± 0.24

1.36 ± 0.31

 MID(%)

17.61 ± 5.48

14.19 ± 2.90

15.82 ± 4.41

16.73 ± 4.04

 PLT(109/L)

493.00 ± 122.40

517.30 ± 169.72

511.00 ± 180.39

514.10 ± 130.51

 GRAN(109/L)

2.69 ± 1.18

3.62 ± 1.45

2.74 ± 1.08

2.90 ± 0.90

 GRAN(%)

35.80 ± 11.97

39.76 ± 11.84

37.01 ± 10.72

35.39 ± 10.62

 RBC(1012/L)

5.55 ± 1.70

5.92 ± 1.79

5.77 ± 1.37

6.01 ± 1.28

 HCT(%)

44.45 ± 12.36

43.62 ± 12.95

44.01 ± 13.52

59.29 ± 12.65

 MCV(fl)

60.27 ± 10.80

64.38 ± 13.58

65.98 ± 13.23

69.79 ± 8.39

 HGB(g/L)

132.10 ± 32.01

131.50 ± 23.08

135.50 ± 23.33

134.20 ± 28.76

 MCH(pg)

18.70 ± 1.78

18.74 ± 1.44

18.50 ± 1.71

18.38 ± 1.23

 MCHC(g/L)

280.20 ± 9.61

276.00 ± 8.61

274.20 ± 8.06

277.50 ± 6.46

  1. All samples were collected from five rats in each group
  2. aData are given as mean ± SD
  3. ANOVA analysis indicated no statistical significance P > 0.05