From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats
Dose (g/kg/d) | 0 | 80 | 100 | 130 |
---|---|---|---|---|
Females | ||||
0 week | 109.0 ± 5.59a | 109.7 ± 7.70 | 110.3 ± 6.37 | 109.5 ± 6.12 |
1 week | 19.5 ± 6.50 | 18.3 ± 4.93 | 15.8 ± 4.23 | 19.2 ± 5.06 |
2 week | 38.7 ± 10.08 | 37.1 ± 7.84 | 34.7 ± 5.75 | 35.9 ± 7.75 |
3 week | 54.9 ± 7.06 | 56.3 ± 6.63 | 54.1 ± 4.17 | 54.5 ± 8.63 |
4 week | 75.4 ± 11.27 | 76.7 ± 11.98 | 75.3 ± 7.060 | 75.5 ± 11.17 |
5 week | 95.0 ± 11.59 | 99.5 ± 10.85 | 94.2 ± 4.620 | 95.4 ± 13.66 |
6 week | 113.1 ± 13.39 | 117.0 ± 13.33 | 113.5 ± 6.20 | 113.7 ± 16.78 |
7 week | 125.9 ± 11.27 | 130.5 ± 14.74 | 118.2 ± 24.31 | 121.4 ± 26.69 |
8 week | 144.1 ± 14.37 | 141.7 ± 24.10 | 142.4 ± 11.54 | 147.7 ± 20.69 |
9 week | 157.6 ± 14.26 | 156.2 ± 23.75 | 157.1 ± 11.43 | 159.8 ± 20.17 |
10 week | 174.7 ± 12.64 | 173.1 ± 21.59 | 173.0 ± 12.72 | 176.8 ± 20.38 |
11 week | 192.4 ± 13.75 | 188.7 ± 22.59 | 188.5 ± 12.97 | 193.9 ± 19.52 |
12 week | 202.1 ± 26.58 | 204.5 ± 21.15 | 201.2 ± 15.43 | 204.6 ± 29.79 |
13 week | 221.7 ± 19.64 | 216.2 ± 23.10 | 215.1 ± 16.52 | 225.2 ± 20.75 |