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Table 10 Organ coefficient for male rats treated with JDHY granules for 13 weeks

From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats

Dose (g/kg/d)

0

80

100

130

Males

 Heart

0.38 ± 0.051a

0.36 ± 0.051

0.36 ± 0.04

0.37 ± 0.06

 Liver

3.44 ± 0.26

3.75 ± 0.57

3.51 ± 0.63

3.40 ± 0.53

 Spleen

0.22 ± 0.05

0.25 ± 0.03

0.34 ± 0.03

0.22 ± 0.04

 Lung

0.68 ± 0.14

0.62 ± 0.05

0.70 ± 0.05

0.71 ± 0.11

 Kidney

0.62 ± 0.14

0.66 ± 0.06

0.71 ± 0.07

0.70 ± 0.10

 Brain

0.48 ± 0.09

0.56 ± 0.09

0.52 ± 0.08

0.49 ± 0.09

 Thymus

0.10 ± 0.04

0.09 ± 0.02

0.10 ± 0.03

0.10 ± 0.03

 Renicapsule

0.02 ± 0.02

0.02 ± 0.01

0.02 ± 0.01

0.01 ± 0.03

 Orchis

0.51 ± 0.16

0.49 ± 0.20

0.41 ± 0.14

0.49 ± 0.14

 Epididymis

0.20 ± 0.09

0.27 ± 0.07

0.26 ± 0.05

0.24 ± 0.09

  1. All samples were collected from five rats in each group
  2. aData are given as mean ± SD
  3. ANOVA analysis indicated no statistical significance P > 0.05