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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Effects of Mollugo pentaphylla extract on monosodium urate crystal-induced gouty arthritis in mice

Fig. 4

Effects of MPE on the expression of cytokines in the paw tissue of mouse with MSU crystal-induced gouty arthritis. Con, control mice; MSU, MSU crystal-induced mice; MPE, MSU mice treated with 150/300 mg/kg of MPE; Col, MSU mice treated with 1 mg/kg of colchicine. Expression of a IL-1β, b TNF-α, c NF-κB, d NALP3, e ASC and f Caspase-1 mRNA was determined by real-time RT-PCR. The mRNA expression levels were normalized to GAPDH mRNA level. Data are presented as the mean ± SEM (n = 5). #p < 0.05 and ##p < 0.0001 vs. control group; * p < 0.05, *** p < 0.001 and **** p < 0.0001 vs. MSU group

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