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Table 1 Mean number of revertant colonies per plate (±SD) in Salmonella typhimurium TA98, TA100 and TA102 exposed to different concentrations of the compounds isolated from C. microphyllum to measure mutagenicity

From: Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts

Concentration μg/ml

500

50

5

S. typhimurium TA98

 n-Tetracosanol

30.00 ± 7.81

35.67 ± 9.71

23.67 ± 4.51

 Eicosanoic acid

27.77 ± 1.53

29.33 ± 4.04

28.67 ± 5.51

 Arjunolic acid

33.00 ± 2.65

28.33 ± 3.78

26.67 ± 1.15

Negative/solvent blank

28.60 ± 5.32

Positive 2 μg/ml 4-NQO

239.33 ± 33.20

S. typhimurium TA100

 n-Tetracosanol

125.00 ± 8.18

121.33 ± 2.52

127.00 ± 7.21

 Eicosanoic acid

108.67 ± 5.03

102.67 ± 4.73

112.33 ± 2.89

 Arjunolic acid

109.00 ± 8.72

104.33 ± 2.52

107.33 ± 1.15

Negative/solvent blank

107.00 ± 4.85

Positive 1 μg/ml 4-NQO

864.00 ± 9.77

S. typhimurium TA102

 n-Tetracosanol

294.33 ± 20.74

271.00 ± 4.58

286.67 ± 8.50

 Eicosanoic acid

292.33 ± 5.51

278.33 ± 7.57

288.00 ± 10.82

 Arjunolic acid

287.00 ± 15.39

280.67 ± 10.69

288.67 ± 28.68

Negative/solvent blank

282.40 ± 15.53

Positive 1 μg/ml MMC

1241.67 ± 7.77