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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Effects of Chinese medicinal herbs on expression of brain-derived Neurotrophic factor (BDNF) and its interaction with human breast cancer MDA-MB-231 cells and endothelial HUVECs

Fig. 5

Effects of Chinese herbal extracts (CHE) on the expression levels of migratory proteins using MDA-MB-231 cells. Cultured MDA-MB-231 cells without/with a CHE (1 μg/mL for each herbal extract) pretreatment were lysed and the expression levels of various proteins related to migration, namely Rac 1/2/3, CDC42, Rho (a) and COX2, MMP2 and MMP9 (b) were analyzed by Western blot. A similar process was carried out for two angiogenesis related proteins, namely VEGFA and VEGFR2 (c) The results are expressed as mean + SEM. *, p < 0.05 compared to the vehicle group by repeatedly measured one way ANOVA; #, p < 0.05 by Student’s t test (n = three to five independent experiments in each group)

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