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Table 2 Sensitivity analyses of Risk Ratio (RR) low risk of bias data subset by a) removing ATBC study, and b) adding fictitious dataset to original low risk of bias trials

From: Validity of a Cochrane Systematic Review and meta-analysis for determining the safety of vitamin E

Analysis

Vitamin E

n/Na

Control

n/N

ATBC Weighting

Low bias Subgroup RR

95% CIs

P value

Figure

Per Bjelakovic A11

11,689/97523

7561/73721

42.6

1.03

1.00–1.05

0.04

S1

Per Bjelakovic A11 minus ATBC 2003Low

6256/82959

4956/66434

0.0

1.01

0.98–1.05

0.44

S2

Per Bjelakovic A11 plus Fictitious Trial

12,664/195046

8298/147442

40.0

1.03

1.00–1.05

0.04

S3

  1. an/N – number of deaths/total number of participants