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Table 2 Effect of extracts SNE, haloperidol (HAL) and vehicle on the duration of catalepsy

From: Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis

Treatment (mg/kg)

Time (s)

 

15th min

30th min

60th min

Vehicle

0.000 ± 0.00

0.00 ± 0.00

0.00 ± 0.00

-

SNE 100

0.000 ± 0.00

2.038 ± 2.04

2.448 ± 1.05

 

SNE 300

0.000 ± 0.00

2.146 ± 2.15

5.862 ± 2.95**

SNE 1000

0.000 ± 0.00

0.000 ± 0.00

1.690 ± 1.69

HAL 0.3

34.187 ± 8.01

87.902 ± 33.81

108.892 ± 32.84

 

HAL 1.0

154.340 ± 42.16**

153.273 ± 52.08*

125.403 ± 55.14*

HAL 3.0

162.660 ± 46.41**

179.510 ± 50.24**

192.122 ± 40.87**

  1. Data are mean ± SEM (n = 5). *P ≤ 0.05, ** P ≤ 0.01, compared with vehicle group (two-way ANOVA followed by a Bonferroni’s posthoc test)