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Table 4 Changes in cytokine expression from bone marrow cells by EPR

From: Aqueous extract of Phragmitis rhizoma ameliorates myelotoxicity of docetaxel in vitro and in vivo

Cytokines

Control

Relative expression (fold)

EPR(2)

EPR(20)

EPR(200)

IFNγ

1.0±0.1

1.5±0.1*

5.9±0.3***

2.5±0.0***

IL1β

1.0±0.1

2.0±0.1***

2.4±0.0***

4.1±0.1***

L6

1.0±0.0

0.4±0.0***

0.3±0.0***

0.3±0.0***

IL7

1.0±0.3

0.7±0.2

1.1±0.1

1.2±0.2

IL12β

1.0±0.1

1.0±0.2

1.1±0.1

0.9±0.1

TNFα

1.0±0.0

1.0±0.0

0.8±0.1

1.0±0.3

  1. Relative expression was determined by comparing to normal control. Data are presented as means±SEM of triplicated experiments. *, ** and **, p<0.05, p<0.01 and p<0.001 vs. vehicle-treated control