Table 3 Hematological effect of EPR in docetaxel-induced myelosuppressed mice
From: Aqueous extract of Phragmitis rhizoma ameliorates myelotoxicity of docetaxel in vitro and in vivo
Treatment | WBC (x106/ml) | Neutrophils (x106/ml) | Lymphocytes (x106/ml) | RBC (x109/ml) | Hemoglobin (mg/dl) | Platelets (x106/ml) |
|---|---|---|---|---|---|---|
Control | 3.44±0.24 | 0.48±0.02 | 2.88±0.23 | 9.11±0.18 | 13.64±0.23 | 659±13 |
DTX+Vehicle | 2.09±0.19*** | 0.30±0.01*** | 1.56±0.22*** | 7.72±0.15*** | 11.96±0.29*** | 1085±46*** |
DTX+EPR(30) | 2.52±0.15** | 0.47±0.06## | 1.83±0.10*** | 8.04±0.13*** | 12.23±0.13*** | 992±71*** |
DTX+EPR(100) | 2.59±0.13**,# | 0.41±0.06 | 2.09±0.10**,# | 7.88±0.13*** | 11.94±0.21*** | 999±48*** |
DTX+EPR(300) | 2.84±0.30 | 0.42±0.07 | 2.22±0.25 | 8.11±0.18*** | 12.39±0.25** | 949±59*** |