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Table 3 Hematological effect of EPR in docetaxel-induced myelosuppressed mice

From: Aqueous extract of Phragmitis rhizoma ameliorates myelotoxicity of docetaxel in vitro and in vivo

Treatment WBC
(x106/ml)
Neutrophils
(x106/ml)
Lymphocytes
(x106/ml)
RBC
(x109/ml)
Hemoglobin
(mg/dl)
Platelets
(x106/ml)
Control 3.44±0.24 0.48±0.02 2.88±0.23 9.11±0.18 13.64±0.23 659±13
DTX+Vehicle 2.09±0.19*** 0.30±0.01*** 1.56±0.22*** 7.72±0.15*** 11.96±0.29*** 1085±46***
DTX+EPR(30) 2.52±0.15** 0.47±0.06## 1.83±0.10*** 8.04±0.13*** 12.23±0.13*** 992±71***
DTX+EPR(100) 2.59±0.13**,# 0.41±0.06 2.09±0.10**,# 7.88±0.13*** 11.94±0.21*** 999±48***
DTX+EPR(300) 2.84±0.30 0.42±0.07 2.22±0.25 8.11±0.18*** 12.39±0.25** 949±59***
  1. Data were presented as means±SEM of n=10 mice. **, p<0.01 vs. control; #, p<0.05, ##, p<0.01 vs. DTX+Vehicle treated group