Fig. 7
From: Aqueous extract of Phragmitis rhizoma ameliorates myelotoxicity of docetaxel in vitro and in vivo
In vitro toxicity of Phragmitis rhizoma extract in normal cells. a Normal human lung fibroblast (IMR-90), neonatal foreskin fibroblast (HFFn), endothelial (HUVEC) cells were exposed to serially diluted EPR. The relative cell viabilities were determined after 48 h compared with vehicle treated cells. b Human hepatic cell line, HepaRG, was treated with serially diluted EPR for 24 h. Cell viability, intracellular GSH content, caspase 3/7 activity and LDH release were quantified as described earlier after 24 h drug treatment. Data are represented as means ± SEM of duplicated (a) or triplicated (b) experiments