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Table 6 Activity against promastigotes and intracellular amastigotes of Leishmania donovani, cytotoxicity in J774G8 macrophage cells of active fractions

From: Evaluation of antimycobacterial, leishmanicidal and antibacterial activity of three medicinal orchids of Arunachal Pradesh, India

Plant fractions

Promastigote IC50 (μg/mL)

Amastigote

IC50 (μg/mL)

J774.G8

CC50 (μg/mL)

RrR Et2O

56.04 ± 0.20

18.42 ± 0.26

97.2 ± 1.2

SnP n-Hex

76.32 ± 2.30

23.80 ± 0.73

89.4 ± 4.7

SnF n-Hex

65.64 ± 0.22

22.16 ± 0.99

100.7 ± 1.7

  1. Data is presented as the mean ± SD of three independent experiments
  2. IC 50 inhibitory concentration of 50% parasites, CC 50 cytotoxicity concentration of 50% cells