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Table 5 Protective effect of B.orthobotrys on hematological profile in normal and experimental rats (n = 5, Mean ± SEM)

From: Anti-arthritic activity of aqueous-methanolic extract and various fractions of Berberis orthobotrys Bien ex Aitch

Hematological parameter Arthritic control Normal control Standard (Aspirin) Aqueous- methanolic extract n-butanol fraction Ethyl acetate fraction Aqueous fraction
Hb
(g/dl)
9.36 ± 0.145 14.26 ± 0.240*** 12.60 ± 0.058*** 13.40 ± 0.115*** 13.36 ± 0.176*** 12.63 ± 0.133*** 11.70 ± 0.115***
RBCs
(× 106 / μl)
4.97 ± 0.079 7.42 ± 0.266*** 6.72 ± 0.133*** 6.80 ± 0.038*** 6.53 ± 0.104*** 6.30 ± 0.038*** 5.78 ± 0.059**
WBCs
(× 103 / μl)
9.43 ± 0.203 5.23 ± 0.120*** 7.70 ± 0.208*** 6.20 ± 0.265*** 6.80 ± 0.346*** 7.50 ± 0.208*** 8.50 ± 0.058*
Platelets
(× 103 / μl)
1225.00 ± 105.39 311.00 ± 3.215*** 732.33 ± 4.631*** 394.00 ± 3.512*** 492.33 ± 3.528*** 591.66 ± 2.728*** 692.00 ± 3.786***
ESR
(mm / 1st h)
20.33 ± 0.882 3.00 ± 0.577*** 12.33 ± 1.202*** 9.00 ± 0.577*** 11.00 ± 0.577*** 12.33 ± 0.882*** 15.00 ± 0.577**
RF
(IU / ml)
48.33 ± 2.028 14.00 ± 0.00*** 25.33 ± 2.333*** 20.00 ± 1.155*** 25.66 ± 0.882*** 32.66 ± 1.453*** 35.33 ± 1.764***
  1. The statistical analysis was done with one-way ANOVA followed by Dunnett’s multiple comparison test. *** = p < 0.001, ** = p < 0.01, * = p > 0.05 compared with arthritic control